I've had issues with my kidneys for a number of years, so I've avoided orals for the most part. The functions can often show up "borderline" regarding the doctor's desired ranges. I get the functions tested app. every four months, and four months ago they showed a marked improvement, better than in a long time. This was following a 16 week cycle of mainly Sustenon and a mastoprop cutter, and also a run of GH. So just last week I went through the same routine of tests and they showed a big downturn with some, like the creatnine level, and GFR. I had just finished an app. 5 week cycle of a very potent Tri-Tren and Test E., which spiked my strength up big time. Unfortunately my blood pressure also spiked up, so now I'm really wondering if that run of Tri-Tren had something to do with the worse kidney results? I'm very aware that high blood pressure has a direct effect on the kidneys, and now wondering if that Tri-Tren was the culprit. For the past 5 weeks my BP has been averaging in the 180s over 80's, when through the summer it was consistently almost 120 over 68 or so........