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  • Results 1 to 9 of 9

    Thread: Not fully understanding rebound

    1. #1
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      Not fully understanding rebound

      My question seems fairly specific, but i could not find ananswer after searching.
      Standard usage seemsthat aromasin is generally 12.5eod, or ed for matter, to control sides(estrogen)..ok fair enough. Standard pct begins clomid and nolva atstandard dosing. ok...I get that. I understand what each compound does and whyit is used and the difference between a SERM and an AI. My question is, ifaromasin is a type I suicide inhibitor, what is preventing rebound of estrogenin the pct if aromasin in not included in pct? I'm obviously missing somethingand quite frankly I'm embarrassed i'm unable to locate the answer myself. Does anyone have alink/advice that could help out in understanding this?
      Thanks for any help.

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      ok if I am understanding your question from what I have gathered over hours and hours of reading .clomid and nolva are used in such a manner to control estrogen levels as your normal test levels increase your body will naturally start decreasing estrogen hence why after a certain amount of time you cut the doses of nolva/clomid downthe whole thing is keeping your body's body in balance . that's why u take a pct to control estrogen levels . the easier it is to maintain test and estrogen levels as u ease out of a cycle the more gains u keep and u will also not crash and feel better . I hope I answered in a way that u can understand . I am no med student lol

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      I wouldn't worry too much about rebound with Aromasin. Most users report rebound issues with the discontinuation of Arimidex.

      I don't think any brothers here would tell you not to take an AI during PCT. It can't hurt and if you have it you might as well just keep taking it.

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      Not fully understanding rebound

      Rebound is more common with arimidex/letro, as the stuff is very good at killing estrogen, and generally brings most users below normal levels or homeostasis, hence the rebound is your body trying to fix what you over-did with the guy who told you to take arimidex at .5mg ed.

      An AI slows down the conversion of estrogen in your system when on cycle. This is a different process than what SERMs do and is not necessary on pct if you are already planning to use nolva. That being said, if you aren't sensitive to estrogen binding in the breast tissue, you very well can pct with said aromasin/clomid.

      Clomid (serm) is used post cycle to block estrogen which signals stimulation to the FSH and LH - very important for PCT don't neglect it - which helps to increase our natural test.

      Nolva's (serm) main use is to block estrogen from binding to breast tissue, it's a breast cancer drug. Since nolva does not show strong evidence that it's effective at increasing natural testosterone, I would strongly advice against nolva only pcts. In my opinion, and AI and Nolva are interchangeable (ONE OR THE OTHER) in the pct plan, but clomid is not.

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      I hope i don't offend anyone who answered but you all are wrong and OP is correct. You do need to worry about estrogen rebound on PCT while using Nolva. Nolva is NOT and AI and is NOT interchangeable with Aromasin or Arimidex or Leteo. Nolva will block estrogen from binding to CERTAIN sites such as breast tissue while allowing it to circulate freely throughout the body. Aromasin will Actually kill the estrogen and Adex/Letro will deactivate it for a certain period of time. aromastise inhibitors (Aromasin/Arimidex/Letro) ARE COMPLETELY DIFFERENT THAN NOLVA/CLOMID and Aromasin is the AI that should be used while on PCT not Adex.

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      Where do you get this information to confidently call everyone wrong? It was laid out in the post above differentiating the two meds.

      Also, why is nolva and aromasin not interchangeable for post cycle therapy? I specifically said nolva was intended for those sensitive to estrogen build up in breast tissue. If not, aromasin is a fine choice for continued use in pct.

      Please explain.

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      wow I was wrong all the way around lol

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      I guess it's my turn to chime in a bit:

      I'm not quite sure I fully understand your question in it's entirety, but Nolvadex routinely binds to estrogen receptors, preventing an estrogen rebound. Clomiphene alone can as you say, "can cause a rebound".....(Or in theory not prevent a rebound). Exemestane will do nothing at all to stimulate your HPTA, but in the lack of Nolvadex, you could implement Exemestane if you feel this would be an issue. Clomiphene has a shorter half-life than Nolvadex, so Nolvadex will be active a few days after you end Clomiphene. It is however advisable to run Nolvadex an additional week; (preferably two) past ending Clomifene just for this reason you are inquiring.



      Last edited by Apex Peptides; 07-28-2015 at 10:40 PM.

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      Run all three Nolvadex clomid and aromasin in your pct

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