Thread: AI and gyno

If gyno has started up, will upping AI dose do anything tohelp it at that point? Can Nolva stop/cure gyno? Can you use nolva + AI at thesame time, or will it decrease the power of the AI? Does lower estrogen makethe serm more effective? I Keep seeing people say don't use AIs for gyno but Iwould think having lower estrogen PLUS the serm you would have a better outcomeas opposed to Slightly elevated E2 and a serm. I’m just trying to sort all of this out.

here were a lot of questions so I'll try to answer them all.

1. Yes, if you started to develop gyno you should up you're AI dose.
2. No, you should NOT use Nolva to stop the gyno. All Nolvadex does is block estrogen from hitting the receptors, you need to actually lower the estrogen.
3. You do NOT need to take an AI and Nolva at the same time - an AI is sufficient.
4. Taking Nolvadex with some AI's will reduce the effectiveness of the AI.
5. Lowering estrogen does not make a serm more effective and you should not take a serm on cycle - there is not reason for it.

Gayno is directly related to high estrogen levels, which means it's an estrogen related side effect. If this happens you need to lower the amount of estrogen in your body. Anyone who tells you to just use Nolvadex is wrong because Nolvadex is NOT an AI and does not lower estrogen at all.

Nolvadex is a SERM - selective estrogen receptor modulator. The primary function of nolva is to stop estrogen aromatization in breast tissue. It's a breast cancer drug, and in our world, means it's our number one tool for combatting estrogen related gyno. To tell this brother that nolvadex would be ineffective here is harmful information.

If things are getting bad with your gyno symptoms, I suggest stopping your cycle and beginning pct with nolva/clomid asap. This is your safest bet.

Since I doubt you will do this, because I am a realist, what is your AI of choice and current dosing?

Once again you are either giving out wrong or incomplete information!!!!!!!! he should not and no one should use Nolvadex on cycle for gyno and it is NOT the number one tool for combating Gyno - an AI is!!!! As I clearly stated above, gyno is directly related to elevator estrogen levels and you need to lower those estrogen levels in your entire body and not just worry about blocking the estrogen from hitting the beast tissue receptor

There are many negative side effects of having high estrogen other than gyno and your method of just taking Nolvadex does nothing to address any of them.

So, it looks like you're the one who is giving out the wrong/harmful information!!!!

I've never tried armidex been interested in trying it out while on a cycle

Originally Posted by bulk_cut

Once again you are either giving out wrong or incomplete information!!!!!!!! he should not and no one should use Nolvadex on cycle for gyno and it is NOT the number one tool for combating Gyno - an AI is!!!! As I clearly stated above, gyno is directly related to elevator estrogen levels and you need to lower those estrogen levels in your entire body and not just worry about blocking the estrogen from hitting the beast tissue receptor

There are many negative side effects of having high estrogen other than gyno and your method of just taking Nolvadex does nothing to address any of them.

So, it looks like you're the one who is giving out the wrong/harmful information!!!!

Nolva and/or raloxifene (both serms) have been proven to be far more effective at shrinking gyno than an AI. AI's are a preventative measure, but some people are sensitive to gyno and will get it even at normal e2 levels....in this case a SERM would be far more useful instead of driving e2 into the ground.

AI's only lower e2, but if gyno is already present you need a SERM to bind to the e2 receptors in the breast tissue to block the effects of e2 and shrink the lump.

Originally Posted by Jozifp103

Nolva and/or raloxifene (both serms) have been proven to be far more effective at shrinking gyno than an AI. AI's are a preventative measure, but some people are sensitive to gyno and will get it even at normal e2 levels....in this case a SERM would be far more useful instead of driving e2 into the ground.

AI's only lower e2, but if gyno is already present you need a SERM to bind to the e2 receptors in the breast tissue to block the effects of e2 and shrink the lump.

Agree with this. I have no science, only personal experience. Had a flare up in the first few weeks of my current cycle. Nolva for a week to get the lump to go away. Increased my AI dose for the remainder of the cycle to keep it from coming back. AI is preventative, but once your prevention has failed, the Nolva seems to help correct the problem, and increasing the AI prevents it from reoccurring.

Those are a lot of questions. lol Are you suffering from gyno right now, or are these questions just for personal knowledge?

In any event; first, you need to control the E2 conversion by finding the proper balance with your AI while on cycle. The BW you SHOULD acquire will help guide you. Yes, you can use nolva at the same time as your AI to help remedy the gyno. However, it is thought that serms can slightly impact the effectiveness of your AI. That being said, lower E2 won't increase effectiveness of the SERM, it'll simply reduce the number of aromatase enzymes capable of synthesizing estradiol in turn reducing the likelihood of it binding at the receptor site. For some people, there's no need for an AI to remedy gyno. SERMs should keep that in check unless your E2 is elevated. If this is the case, dosing of AAS may need to be adjusted if possible or consider adding in an AI (which you should have done regardless). Running both (SERM and AI) together isn't a problematic if it's certainly needed, but I always try to use the least amount of compounds necessary.....ya know... Less = More.

I hope I'm not too far off...just a few of my thoughts.

I hope this helps!

I don't have gyno...I'm just asking to develop a better understanding.

Thanks guys!!