Thread: Melatonin - Potent AI?

Check out this research, where melatonin, reservatrol and letrozole were added into breast adipose tissue in vitro.

As we know, aromatisation of testosterone to estrogen can occur at the aromatase enzyme in fat cells.

Both melatonin and reservatrol were found to act as aromatase inhibitors in this co-culture model, however, melatonin was 1000x more potent than reservatrol.

The most surprising finding here was that melatonin was equally as potent as letrozole!

Anti-aromatase effect of resveratrol and melatonin on hormonal positive breast cancer cells co-cultured with breast adipose fibroblasts - ScienceDirect



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Wtf damn
How much of it though

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Originally Posted by 350zsidewayzz

Wtf damn
How much of it though

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This is in vitro research, so we have no idea right now how applicable this is to a human model. We can hypothesise it is pretty effective though. Follow the research for dose information


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