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Originally Posted by
Weapon X
Don't profess to be the expert. That said, and I could be dead wrong, grapefruit juice doesn't make oral AAS more hepatotoxic just increases their bioavailability. Now, quite possibly having more bio available AAS may have increased hepatotoxic effects? I know what you're saying but I'm just trying to point out a difference. Meds will tell you to avoid taking grapefruit juice for those affected by CYP34A inhibition because they can cause a lot stronger reaction than dosed for.
Honestly brother I'm no expert either but making a hepatoxic drug more bio available just seems like it's gonna do more damage. I'm just trying to make an educated guess I could be wrong
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yeah pretty sure it makes the liver work harder. when u ingest non methylated compounds they dont survive the liver and they dont do much effects or damage. when u methylate? them they survive the liver and u get problems. so i think it makes it harder on the liver.
the enzyme responsible for breaking the chemical down cant do its job so more of it sits in the liver. this is bro science though i havent done much research on bioavailability
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With all the crazy stuff we do, there's nothing wrong with exercising due caution
Originally Posted by
joko123
Honestly brother I'm no expert either but making a hepatoxic drug more bio available just seems like it's gonna do more damage. I'm just trying to make an educated guess I could be wrong
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