Thread: Npp vs deca

Is there any gain advantage of deca over npp? Other than pinning eod. I know the diffence is just the ester but some claim better gains from deca. To me the science doesn’t support this. Just wanted the opinion of brothers with more experience than I.

Originally Posted by Jayjaytocool

Is there any gain advantage of deca over npp? Other than pinning eod. I know the diffence is just the ester but some claim better gains from deca. To me the science doesn’t support this. Just wanted the opinion of brothers with more experience than I.

What I notice for myself and many others is the clearance time better assists with less sides..I'll explain!

As we should all know people will possess different amounts of enzymes different genetics and so on.. Now where does clearance time with the ester come into play? Basically there's precursors throughout the body and these can be found in all sorts of tissue including adipose tissue, yes FAT TISSUE..When a hormone simulates (not duplicate, but simulate) the effects of T it can awaken "storage like cells" or even receptors that will react as if the presence of a specific hormone is about..Now some people stress that nandrolone and even some agents like Drol doesn't aromatize nor can it activate estro metabolites but how does one get estro like sides?!?! In principle it's said that some AAS won't convert however it's been proven that in some instances "mostly rare" that this can in fact take place outside of what we know as "normal aromatization", there's a vast amount of transformations in the body..Some aas have been transformed within their positions to avoid this, and others by delivery method (attempting to avoid the stomach by way of enzymes, and gastro tracks or even directly with the liver)..
Yet we still see this effect of estro like sides and a interplay with the PG receptors (Progestin levels elevates and/or secreted) ..A lot has to do with it's loitering time for a good amount of compounds but not all, it's detailed expression with clearance mechanisms, the longer a certain drug is present the greater the chances for metabolites to be activated despite "some" ring positions and its group, here lies the problem for some, regardless if a drug is said that it can be transformed or even if an enzyme is blocked or occupied, estrogen can be produced in small amounts via other tissue like the liver and fat cells as an example.. This can take way merely by a molecule that resembles an other and there hosting receptor sites may react and in fact sensitize and or other tissue my secrete and produce, ER's are now activated and now they initiate PR's and so on..It's a chain of events with enzymatic reactions regardless of the most parenting hormone, there's a host of tissue that can synthesize and secrete into the blood, unbeknownst to any AI and still have reactions at REC's.. The greatest question in biochemistry has always been "is there a way to prevent unwanted metabolic conversions"? They've done this by the modulation of chemical structures or/and there positions, with that said it's a testament in its own that even science can't fully manipulate or dictate biosynthesis..Bear in mind depending on the integrity of the bond and how easy aromatisation reaction catalyses by way of aromatase enzyme may be, some bonds are simply impossible to see aromatisation for geometrical reasons or even display activities that may resemble estrogenic like proprieties (masteron, proviron and even stenbolone would be great examples).. Does this make any sense? It's truly an individual case to case basis with most AAS..

Now with this side, in my own personal experience that loitering time and drug clearance plays a pivotal role with the activation or transgression by way of secondary aromatase reactions and cellular/enzymatic awakening having influences over ER & PG receptors..

NPP is my go to compound when attempting to keep the muscle belly full at the same time avoiding estrogenic like effects like water retention and so on..

From what I've gathered from users (including myself) over the years or seen in studies and anecdote reports, heavier/long esters have a tendency to bring more sides, shorter the ester it decreases your odds of experiencing anything unwanted..

I have gyno on both pecs. Deca aggravates it enormously. I may try that blend you use and see how it feels

Originally Posted by BadGas

You do not need to pin NPP every other day if you do not want to..

Deca is great .. Its' long lasting .. takes a while to kick in.. but with longer lasting esters.. comes the chance for unwanted side effects.. (ie bloating from water retention, gyno, erectile issues, etc).

NPP is considered a shorter ester.. It's in and out... Meaning after day 1 of the injection, you're already seeing a decrease in levels... By about day 4-5, you've hit the half life mark.. So you have about 50mgs left in your system. This short life span.. versus Deca's long life span.. doesn't allow for compounding effects of the nandrolone.. And hence you're probably never going to see side effects on a EOD or 3x or 2x week schedule..

Ultimately which to use depends on the user .. For me the most important aspect is my health.. I love Deca.. but due to blood pressure issues.. I can't use it the way i use to. When I retain.. my blood pressure goes up instantly.. A lot has to due with diet.. but Deca is one of those that knowingly you retain water..

My winning combination is 100mg NPP and 100mg Deca per week.. thats its.. I use a blend of the 2 on every blast.. sometimes going as low as 50mg of each.. just for the therapeutic benefits.

I think I understand most of what you are saying. Thank you for the detailed response. Mostly is sounds like an advantage for npp. Supporting my current feeling that there is no advantage for deca. Some people claim stronger longer lasting gains. I don’t see any reason other than bro science for this thought.