I have read contradicting information on the effective dosage. I know that some AIDS patients require a minimum daily dose of 40 mg. I found a recent study published in The American Journal of Case Reports where a patient affected by Charcot-Marie-Toot I (CMT-I) disease, a hereditary motor and sensory neuropathy characterized by a severe demyelinating process was treated with 20 mg of Oxandrolone daily for three months.

In addition an exercise training program including isotonic exercises with free weights and isotonic machines with a frequency of 3 times a week, training 2 or 3 muscle groups each session under the supervision of a Health and Fitness Instructor. One exercise for each muscular group was programmed, starting with the minimum effort tolerated.

After the 3-month therapy, the patient gained 5.0 kg of lean body mass. Muscular strength increased significantly: maximum voluntary contraction at bench press increased from 10 to 25 kg, dumbbell fly capacity increased from 2 to 8 kg, and leg press capacity increased from 15 to 40 kg.

The entire study is published in the link: Neuroregenerative Effect of Oxandrolone: A Case Report

I don't know if AIDS patients were asked to participate in resistance training, but here a lower dosage resulted in dramatic gains.

Just some food for thought.

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