I tried sub q a few times and it was pretty painless and effortless. For the test, I shot a few throughout the week .5 ml of test enth 250 and no problems. I injected .5 prop 100 - no problems. Once I injected .6 - big problem. lol. I had welts for about 2 weeks. I only tried it twice, but like I said, it was just a test towards the end of my cycle. I could definitely see myself doing that again in the future with test enth. I was running out of places to inject safely, so I figured, why not?