Thread: HOW MUCH TEST DOES THE BODY ABSORB?

I'm wondering if the body absorbs all the test you inject into it.
and if yes what's the limit if there is one?
Let's say i inject 500 mg of test-e will my body absorb all 500mg's

Over time yes, that's all decided upon by the ester which sets the bar for the half-life. If a guy injects 2 grams it will all be absorbed overtime...but at one point does the body no longer use the excess test? where's the "diminishing returns" line.

Tank the more I thought about your question the more I wondered the same thing. My previous post did not supply any kind of answer....so I've been digging and finding some legit info on this is a little harder then I thought ....here's what I've found so far,



•Absorption


Following oral administration of testosterone, only small amounts of the drug reach systemic circulation unchanged. The low bioavailability of orally administered testosterone results from metabolism of the drug in the GI mucosa during absorption and on first pass through the liver. The synthetic androgens (i.e., fluoxymesterone, methyltestosterone) are less extensively metabolized following oral administration.


Esterification of testosterone generally results in less polar compounds. The cypionate and enanthate esters of testosterone are absorbed slowly from the lipid tissue phase at the IM injection site, achieving peak serum concentrations about 72 hours after IM injection; thus, these esters have a prolonged duration of action (i.e., up to 2–4 weeks) following IM administration. Testosterone propionate, however, reportedly has a shorter duration of action than that of testosterone following IM administration. Because IM injection of testosterone or its esters causes local irritation, the rate of absorption may be erratic.


Following subcutaneous implantation of testosterone pellets, approximately 33% of an implanted dose is absorbed systemically during the first month, 25% during the second month, and 17% during the third month. The duration of action of subcutaneous testosterone implants (pellets) is usually 3–4 months but occasionally may be up to 6 months.


Testosterone is absorbed systemically through the skin following topical application as a gel or transdermal system. Following topical application of a hydroalcoholic gel formulation of testoterone (AndroGel® 1%) to the skin, the gel quickly dries on the skin surface, which serves as a reservoir for sustained release of the hormone into systemic circulation. Approximately 10% of a testosterone dose applied topically to the skin as the 1% gel is absorbed percutaneously into systemic circulation. The manufacturer states that increases in serum testosterone concentrations were apparent within 30 minutes of topical application of a 100-mg testosterone dose of the 1% gel, with physiologic concentrations being achieved in most patients within 4 hours (pretreatment concentrations were not described); percutaneous absorption continues for the entire 24-hour dosing interval. Serum testosterone concentrations approximate steady-state levels by the end of the initial 24 hours and are at steady state by the second or third day of dosing of the 1% gel. With daily topical application of the 1% gel, serum testosterone concentrations 30, 90, and 180 days after initiating treatment generally are maintained in the eugonadal range. Following discontinuance of such topical therapy, serum testosterone concentrations remain within the normal range for 24–48 hours but return to pretreatment levels by the fifth day after the last application. The manufacturer states that mean concentrations of the active metabolite dihydrotestosterone (DHT) were within or about 7% above the normal range 180 days after initiating daily topical application of 50 or 100 mg, respectively, of testosterone as the gel. Increases in DHT concentrations appeared to parallel those of testosterone, and the mean steady-state ratio of DHT to testosterone was maintained in the normal range during the 180-day treatment period.


This entire article was a very good and LONG read related to test. It contained almost everything you could wanna know, but even here there is no #'s put to paper regarding IM shots....I'm continue to dig

Thanks dath good read. I'm thinking there has to be a limit to how much test your body absorbs