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Lastly, and remember I am just repeating what he says...
That no one should use an AI. He doesn’t even allow his IFBB guys he over sees to use them. The only time is close to contest time and that’s it! After that, maybe for a few wks, they come off them.
He recommends always using Masteron or Proviron as a way to assist in e2 control as it doesn’t block it nor effect the liver etc.
He says that is what and why Masteron was originally developed for.
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Originally Posted by
GoGoGodzilla
No doubt Pcushion knows his shit and Basic is a solid reputable source, the water weight thing has caught my attention and am definetly thinking of giving it a go? I don’t run any AI now as I have never needed to but when I run longer esters I hold a bit of waster and I am currently on TestU and TrenH. Now after some quick googling I see the name Torem is used for two separate medications. One being a diuretic (Torasemide) and the other being a Fareston (Toremifene). I don’t see any claims of Fareston controlling water weight... Hoping you can elaborate on the Benefits of your Fareston?
So I use toremifene. Ability to control water weight is an off label thing. In the human body you have two estrogen receptors alpha and beta. These have different biological functions. So what torem is able to do is provide or deni selective stimulation to estrogen pathways in various target organs. Determining the balance of activity between erA and erB will decide what estrogen effects manifest. The epithelium is primarily erB expressive. So in conclusion torem interacting with erA causes the activity balance between A and B to promote normal fluid retention.
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Originally Posted by
thebear
This guy is an ex IFBB and now a cardiologist, fucking knowledgeable cat for sure.
He says any AI (adex, asin) are dangerous. Most of the studies showing their effect on...
Brain tissue
Brain cells
Synovial fluid
Bone density
Lymphatic fluid
CSF
Mineral balance
Arteries
The liver
were not published so big ****** could make money. He was part of some of the research himself.
I asked about Torem....
“it has estrogenic effects in the liver, because of its major side effect (blood clotting) and (high blood calcium ) increases plaque in the arteries, its a hands off drug for my Cardiology patients. Bodybuilding wise because of the high estrogenic effects in the liver and extremely high liver enzymes I wouldn't recommend it to anyone, bb is about keeping the liver operating at the highest efficiency blocking to much estrogen has a detrimental effect in the body, estrogen is necessary for proper muscle development, can't over block a natural body function without creating more serious problems!!!”
If the guy is a cardiologist he knows more than I do. My first thought though is that torem has been shown to increase the risk of dvt and pe in those with genetic predisposition but not nearly the extent nolva does. It is estrogenic in the liver but this activity promotes positive lipid values. I do not believe torem would be the culprit when it comes to elevated liver enzymes especially in a bodybuilder. I think oral steroids would be the cause for that and the torem might not help.
Originally Posted by
thebear
Lastly, and remember I am just repeating what he says...
That no one should use an AI. He doesn’t even allow his IFBB guys he over sees to use them. The only time is close to contest time and that’s it! After that, maybe for a few wks, they come off them.
He recommends always using Masteron or Proviron as a way to assist in e2 control as it doesn’t block it nor effect the liver etc.
He says that is what and why Masteron was originally developed for.
Yeah masteron was shown to interact not only with the E2 receptor but also aromatase enzyme effectively blocking E2 effects while also providing a more androgenic environment. We are not sure why or how masteron does this though. I also agree with no AI use and also agree with mast as estrogen control. The body likes balance so a body builder running a dht derivative beside his test based hormones and 19 nors will be happier and feel better than the one without. Provi is hit or miss with E2 control. It plasma protein binding capabilities subsequently elevate circulating estrogens in the body.
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Originally Posted by
thebear
Lastly, and remember I am just repeating what he says...
That no one should use an AI. He doesn’t even allow his IFBB guys he over sees to use them. The only time is close to contest time and that’s it! After that, maybe for a few wks, they come off them.
He recommends always using Masteron or Proviron as a way to assist in e2 control as it doesn’t block it nor effect the liver etc.
He says that is what and why Masteron was originally developed for.
Ai use too much will block minerals and assure statins... my HDL was 38 to 45 using mast and Nolva zero ai!! Looked back on bloods.
Cardio guy says nolva fine.
Torem has more sides than nolva...
I will go back to mast and Nolva myself
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Originally Posted by
Pcushion
If the guy is a cardiologist he knows more than I do. My first thought though is that torem has been shown to increase the risk of dvt and pe in those with genetic predisposition but not nearly the extent nolva does. It is estrogenic in the liver but this activity promotes positive lipid values. I do not believe torem would be the culprit when it comes to elevated liver enzymes especially in a bodybuilder. I think oral steroids would be the cause for that and the torem might not help.
Yeah masteron was shown to interact not only with the E2 receptor but also aromatase enzyme effectively blocking E2 effects while also providing a more androgenic environment. We are not sure why or how masteron does this though. I also agree with no AI use and also agree with mast as estrogen control. The body likes balance so a body builder running a dht derivative beside his test based hormones and 19 nors will be happier and feel better than the one without. Provi is hit or miss with E2 control. It plasma protein binding capabilities subsequently elevate circulating estrogens in the body.
My opinion is mast acts as dht and is natty estro defence in body dht is... DHT is backbone structure in aromasin so it's binds and is suicide affective rather competing. Mast was used in breast cancer and effective except maximizing viralizatiin in women. So other options used for women....
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Ever since I read his response on the other forum, I've been very hesitant to use aromasin or really any AI. The thing that scares me most is the drug compromising blood vessels, which he said can cause a heart attack or stroke after years of usage. I'm in contest prep too, so it's hard not to use it. In considering switching to mast instead, but I'm not sure my coach will be on board. I'd be interested to see if mast is enough to keep estrogen at bay. I'm not very sensitive to it, and can get away without using an AI with just about anything other than trest.
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Originally Posted by
solocom
Ever since I read his response on the other forum, I've been very hesitant to use aromasin or really any AI. The thing that scares me most is the drug compromising blood vessels, which he said can cause a heart attack or stroke after years of usage. I'm in contest prep too, so it's hard not to use it. In considering switching to mast instead, but I'm not sure my coach will be on board. I'd be interested to see if mast is enough to keep estrogen at bay. I'm not very sensitive to it, and can get away without using an AI with just about anything other than trest.
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I agree. I think he said contest prep is ok for a few wks closer to contrast to dry out. Then after to drop it.
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Originally Posted by
thebear
I agree. I think he said contest prep is ok for a few wks closer to contrast to dry out. Then after to drop it.
I'm going to pitch that to my coach. He currently has me on aromasin every day. I would think a few weeks before the show should be plenty of time to get rid of any extra water.
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Some research has shown that grape seed extract could prove useful as a natural alternative to be utilized as an AI... I am not the science guru but always keep an eye out for topics like this.. Have any of you brothers heard of this. Here is a quick link to a review of a NCBI abstract.. I'm sure there is more information on this
Grape seed extract is an aromatase inhibitor and a suppressor of aromatase expression. - PubMed - NCBI
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It’s not about stopping the conversion, as it’s needed for many reasons.
It’s about getting rid of unneeded e2. He rec proviron and or mast. But also things like DIM, Indol 3 carbonal etc. or Testolize.
He says if your taking a gram etc of course there will be conversion and it’s almost impossible not to take an AI.
But for TRT not needed.
As well for most of us not needed as well.
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