Quote Originally Posted by Mr Myagi View Post
Great topic. When I was poppin oxy's I did some research and found that grapefruit juice (white) works well. And eat a couple antacids before. But another trick was tonic water with quinine. Guzzle some of that and give it a try. It allegedly helps with rls and leg cramps but I don't know. My wife is gonna think I'm getting stoned again.
I have heard this about the tonic water w/quinine, but have not done extensive research on it. I've heard a lot of anecdote but not read a lot additional on the topic. And yes, I do believe that the same enzyme with which GFJ interferes is associated with metabolization of steroidal compounds is the same one associated with the metabolism of opiates. I don't know how much more we can talk on those lines in this section of the forum, but on a purely scientific plane you're correct.