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  • Results 1 to 10 of 31

    Thread: * * HOW TO DETERMINE AAS HALF LIFE - MEMBER DISCUSSION THREAD * *

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      Exclamation * * HOW TO DETERMINE AAS HALF LIFE - MEMBER DISCUSSION THREAD * *

      On the regular I get asked about the half lives of certain gear and how the half elimination period is determined.

      As far as I know there is a direct correlation between the # of carbons and the half life.

      To start I've provided a list of esters and how many carbons are in the carbon chain. If you have different data or this list is outdated then pls let me know.

      Here's a brief explanation on the knowledge I have to date.

      Steroid esters are a steroid molecule with a carbon chain attached. Each ester is unique having its own # of carbon atoms.

      The carbon chain, is directly involved in determining the half-life of the steroid, and solubility in the bloodstream.

      So let's look at the list that I believe to be most accurate.

      Formate-1 carbon ester
      Acetate-2 carbon ester
      Propionate-3 carbon ester
      Butyrate-4 carbon ester
      Valerate-5 carbon ester
      Hexanoate-6 carbon ester
      Heptanoate-7 carbon ester
      Enanthate-7 carbon ester
      Octanoate-8 carbon ester
      Cypionate-8 carbon ester
      Nonanoate-9 carbon ester
      Decnoate-10 carbon ester
      Undecanoate-11 carbon ester

      The higher the # of carbon atoms in the ester, the less soluble the steroid is in the blood stream, and the longer the half-life. Two enzymes...esterase and hydrolysate...cleave off the carbon atoms from the carbon chain.

      Finally the carbon atoms are removed and the steroid is activated.

      HERE'S WHAT I NEED TO KNOW AND CAN'T FIGURE OUT...."IS THE # OF CARBON ATOMS IN THE CHAIN THE ONLY DETERMINING FACTOR OR IS THERE MORE TO THIS?"

      Pls guys offer up all you know, can find thru a search online, or asking fellow hobbyists. Post any and all you can find. It might seem insignificant only to prove a key piece of the puzzle at a later date.

      This is a thought provoking thread. Meaning I have acquired some knowledge over the last year & a half on the subject of pharmacokinetics for the purpose of knowing how to determine the half/full elimination periods of the AAS we commonly use. If you think I'm wrong or misinformed then I encourage you to show me the inaccuracies or identify the data, I have provided, that is outdated. What would be ideal in that situation is to simultaneously educate me on this subject and tell me exactly how to determine the elimination period so I can do it on my own ......aaaaand my search will end!

      Point is no judgment in this thread or drama. This is for the purpose of seeking knowledge and sharing knowledge. Whatever you've got or can find pls POST IT.

      If an answer is not posted soon then who knows maybe in a few yrs a member will have an answer for us.

      Now let's compile some info......
      Last edited by Riggs; 09-08-2020 at 07:33 AM.

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