Does anybody think there's merit to it? I think it was blasting 5 grams or so for 2-3 weeks with the thought that more androgen receptors would be made.
I remember when I read this it made no sense to me.. I don't understand how you could build more receptors because that's not how your body works with surplus. At least that I know of.. However now there's a study out with the rats about steroids causing life long increase in number of cells within our muscles, therefore allowing substantially more growth potentially forever.
What if Duchaine worded it the only way he knew how, and what he was actually on to was cell proliferation.. Blasting allowed our bodies to create more cells.. More cells = more growth, so your lower dose "normal" seems more effective.
Thoughts on this guys? I mean obviously the dose is pretty crazy and potential for extreme side effects. High doses like that scare me, but is there sound reason and merit behind this? Lets open a discussion.
bigsam
11-29-2013, 08:19 PM
Dan Duchaine was borderline crazy with some of the ideas he came up with.
Dan Duchaine was borderline crazy with some of the ideas he came up with.
Yeah the only one that stands out in my head as something I want to learn more about is this.
enrod
11-30-2013, 12:45 AM
I'm not scientifically versed on androgen receptors. However if I'm not mistaken test does not have the capability to create new muscle fibers (but does increase the size of muscle fibers), as I believe this is what HGH does. Correct me if I'm wrong, could just be an over-simplification of journals I've read.
I'm not scientifically versed on androgen receptors. However if I'm not mistaken test does not have the capability to create new muscle fibers (but does increase the size of muscle fibers), as I believe this is what HGH does. Correct me if I'm wrong, could just be an over-simplification of journals I've read.
Well the recent study in rats showed that steroids caused an increase in cell count, which by my understanding is different than creating more fibers. It should simply mean there are more cells there to grow and swell with glycogen etc etc..
Now we do know IGF-1 increases fibers and that can be done in various ways, Tren is actually shown to increase IGF-1 count within the muscle... But blasting HGH seems to be the most superior way I can find right now. IGF-1 LR3 works a little different when injected solo, it does increase what we want but it seems like circulating so long causes a lot of unwanted things to happen too..
Anyway, off topic, but your question was answered.
Hypertrophy or plasia
Hypertrophy of new cells created via cell proliferation, which by my understanding is a little bit different than hyperplasia, because no new FIBERS are involved. Simply more CELLS within the current fibers, which can grow.
It was likened to creating FAT cells that can store fat. More fat cells = more fat cells to fill up faster.. Same concept except applied to muscle cells.
TheHamburglar
12-02-2013, 12:28 AM
Did you find any information of him putting it through an actual trial?
Duchaine may have been half crazy but the dude was a fuckin innovator. He did things in search of results regardless of what anyone said. I respect him.
Did you find any information of him putting it through an actual trial?
Duchaine may have been half crazy but the dude was a fuckin innovator. He did things in search of results regardless of what anyone said. I respect him.
There are several guys I've been able to find that ran a cycle with his theory.. There was also one pro I read about that did it directly under Duchaine. I'll do some digging after dinner.
I do not know the very original source but here is a quote of one guy I could find..
I am in the process of wrapping up a short 8 week bulker. I've
always been interested in Duchaine's Theory of Post AR Mediated
Growth and what I understand of it, that I tried it during this
cycle. However, I'm not a reckless Duchaine. Much time and energy
went into researching every possible aspect of this cycle theory. I
am not afraid of being a guinea pig as long as I'm an informed
guinea pig. For those of you who don't know, Duchaine's Theory
states that at supraphysiological levels of AAS (especially test)
another growth pathway opens. This is achieved by reaching levels
of 4g-10g of AAS per week. Unfortunately the theory is somewhat
incomplete. I say this because even though Duchaine tested this
many times, he died before he had a chance to get his entire theory
in writing. Information is very hard to find and the biochemistry
behind the new pathway can't be found (at least I can't find it).
IMO this is not what killed him although after doing it hundreds of
times it certainly could have been a factor. I think what
ultimately killed Duchaine is the fact that he was the world's best
AAS/performance enhancing drug guinea pig. Finally things caught up
with him and may he rest in peace.
Anyway, I decided to give this theory a simple test. After
gathering all the research I possibly could, studying, talking with
other bbers, etc, I began my experiment. My 8 week bulker was run
as a standard pyramid with the middle four weeks at
supraphysiological levels. I quickly ramped up to the dosages I
took and then quickly came back down. I'm currently in week 8
preparing for PCT.
During the middle 4 weeks my dosages were as follows: 2.5g test
enan/week, 1g sust/week, 800mg deca (http://www.steroid.com/Deca.php) /week, 150mg finaprop EOD, and
50mg dbol (http://www.steroid.com/Dianabol.php) ED. Approx 4.5-5g of AAS per week.
Results: IMO there is another growth pathway that exists at huge
levels of AAS administration. My receptors had to have been
supersaturated, yet my gains were incredible. For instance at week
5, I was up 35lbs. On week six I started T3 and will run it through
week 9. Right now at week 8 I'm up 45lbs, and I'm continuing to
grow albeit slower because of the fat burning of T3 and my down
ramp.
Thoughts: I'm 100% positive that there is another growth pathway
involved with high AAS administration. The short 4 week "super"
cycle was hard on my body but not as hard as I expected it to be.
My only side was an increase in my BP top number occasionally,
which would not be uncommon under the load I was taking. I will
shortly add all my ancies, supps, etc which I know helped keep
everything together. I'm trying to get this all down so the bbing
community has it. I wish I knew more about the biochemical pathways
of the body. I'm certain the new pathway opens due to dose. I wish
I could explain how the new pathway works. I wish I could explain
what comprises the pathway. In the future, I would not be opposed
to running this again with similar AAS (maybe a few changes) for a
longer period of time. I'd like to run for 8 consecutive weeks at 6-
7g per week with an up ramp and a down ramp. I'd like to run for 16
weeks. However I will not be doing another for quite sometime to
let my body readjust. Currently I will still cycle, but not using
Duchaine's theory (much lower dosages). I would like to wait at
least 9-12 months before attempting this again. I will get blood
work done this time every week. I also would like your guys'/gals'
help. I need help finding a biochemical engineer or a biomedical
engineer, etc who is familiar with AAS that would be interested in
tracking progress during my next "super" cycle. I would like to
find out and explain this new pathway.
Ancies/Supplements: During my entire cycle here are the ancies,
supps, etc I'm taking (I will not include PCT because it will be
pretty standard with the addition of cortisol suppression--Cymbalta
(duloxetine hcl), Nolva, Femera, Remeron, Clomid, HCG (http://www.steroid.com/HCG.php) , Proviron (http://www.steroid.com/Proviron.php) ,
tribus, and ZMA plus reg supps, etc): Femera 1.25mg EOD,
Finasteride .5-1mg ED, Inj L-Carnitine 400mg ED, Inj Tripart 100mg
ED, Inj B-Complex 38mg ED, Inj Adequan 20mg E7D, T3 25mcg weeks 6-9
with dosages adusted by BBT, Synth Gugglesterones one week (10),
Cranberry juice, water, Crystal Light, Gatorade, Powerade,
Glucosamine/Chondroitin 1000mg, MSM 1000mg, r-ALA 250mg 2x/day,
ALCAR 450mg 2x/day, Green Tea Extract 450mg, ON Whey, Micronized
Creatine, Glutamine, Glutamine peptides, Taurine 450mg 2x/day, L-
Arginine 450mg 2x/day, Chromium Picolinate 200mcg, Milk Thistle
450mg, Liv-52 250mg 2x/day, Super ***** 3, 6, 9 EFAs 4000IU 2x/day,
zinc 50mg 2x/day, multivit, vit c 500mg 2x/day, vit e 400IU,
acidolopholous 6mg 2x/day, zanaflex 4-8mg, ultram 150mg, and HCG
250IU 2x per week.
If you have any questions feel free to ask. Also feel free to
provide any and all types of feedback, etc. AND if you know of a
biochemist, biomedical engineer, etc who would be interested or are
a biochemist, biomedical engineer, etc I would be much obliged.
And here are the results:
I had to extend my downramp by four weeks because the body
adjustment is just too much. So I ran my last four weeks with just
test prop and tren (http://www.steroid.com/Trenbolone-Acetate.php) ace.
Please DO NOT try this if you're a newbie or on your fifth cycle,
etc, etc. This is my xxx cycle (lost count), and I went in very
prepared, and I'm coming out very prepared. A great deal of
research and time went into the planning and running of this cycle.
Must add bros that yes, I admit it, I did also run a little Cialis
just to see what would happen during my peaks..........Jesus. All I
can say is you better have multiple nymphos around at your beck and
call because one nympho's (and I don't care how much of a nympho
she is) accessible holes are eventually going to get tired. I'm
dead serious. Either that or have a fun time punching holes in the
wall or beating it to a bloody stump.
Results in total:
Gross weight gain: 45lbs
Net weight gain: 25lbs (this includes a four week T3 cycle within
the bulk cycle)
I had the following tests run after PCT. All were normal with the
exception of cortisol which was low (exactly where I wanted it).
Here are the tests:
Total Cortisol
DHEA Sulfate
IGF-1
IGFBP-3
Free T3
Free T4
TSH
Total Test
Free Test
Weakly Bound Test
Hemoglobin A1C
Fasting Insulin (http://www.steroid.com/Insulin.php)
CBC
CMP
Lipid Panel
GGT
PSA
This article I posted discusses in a more scientific way about how steroids increase cell nuclei.
I feel like this really needs to be discussed with all this evidence.
http://brotherhoodofpain.com/showthread.php?11458-How-Testosterone-permanently-effects-muscle
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