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thebear
11-07-2019, 01:39 PM
Who wants a healthy LIVER?

Everyone right!

If you search this board you will find so many ways to support yourself on a BLAST, on a CRUISE, when taking ORALS or even on just TRT. It seems like everyone has the answer as to what works for them to bring success to their liver/CV lab values.

We see things such as…
TUDCA and NAC while on orals
TUDCA, NAC and Milk Thistle when off the orals

Others swear by…
5% Liver organ defender + TUDCA

I am sure there are a many other ways to support the detox system and liver. But something I recently came upon really peaked some curiosity.

I have some friends on another board who SWEAR by the protocol below and have labs to prove it.

When you are on a blast, esp with orals…
Glutathione injections 100mg M-W-F throughout the length of the cycle.

Then once you are done with the cycle, continue with glutathione but add MIC (Methionine, Inositol, Choline) at 5000mg, 3000mg, 3000mg to rid the liver of fatty tissue that builds up. This is run for 3-4wks.

He mentions that he got this in the past from friends who were PROs and, if you are on slin, at wk 2 of above protocol you might need to cut the slin in half because your system is so fresh that everything will hit a bit harder.

My point in this post is, to share this, to say I am going to try this during my next BLAST containing SDROL.

But to see if others have tried this, know anything about this, etc.

Glutathione Reduced (GSH) – GSH is clinically proven to optimize immune system function, maximize the function of antioxidants, support detoxification process at a cellular level, increase energy levels, and increase strength and endurance. Performs a vital role of repairing damaged DNA from free radicals. GSH detoxifies a large number of pollutants by binding to carcinogens, heavy metals, pesticides and radiation by forming a soluble compound with the toxin that can be excreted through urine or bile.

Some more information below about MIC from Max.

General Information:
Lipo is a mixture of compounds that may aid in the reduction of adipose tissue (fat). The mixture of compounds individually may be effective, however in combination they may exhibit more lipotropic activity than when administered alone in a synergistic fashion. Injection of this mixture of lipotropic compounds may be more effective than oral supplementation, this is due to the increased bioavailability of parenteral exposure.

These lipotropic agents are structurally and functionally closely related to the B-vitamins, or are involved in the homeostasis of energy production from fat. These compounds are often employed together in the hope of potentiating fat-loss, thus while the MIC mixture and B vitamin(s) are often injected separately, they are part of the same overall injection cycle. The non-vitamin compounds (MIC) that are injected into the body stimulate the liver into optimizing the process of metabolism, elevate the movement of and utilization of fat, and provide the needed metabolic environment of the body for a fatty acid (fat) mobilization and utilization.
Typically, these compounds are administered in concert. Injections can be administered up to twice a week.

Lipotropic compounds are used to increase the potential for release of fat deposits in some parts of the body. The lipotropic agents included in this injection are:

Methionine:
Methionine helps the liver maintain the optimal ability to process fatty acids.1*Methionine is a major constituent of S-adenosylmethionine which has been shown to be associated in genetic regulation and activation of certain genes.2*Methionine contributes to methyl donation to histones that activate certain genetic processes that may be involved in the increase in lean tissue. Although indirectly linked to lipolysis, it is believed that the increase in lean tissue increases resting metabolic rate, therefore increasing the overall required calories that must be obtained from storage or dietary intake. Methionine, via S-adenosylmethionine, has been shown in animal models to increase CNS activity, therefore increasing the caloric requirements required by the CNS.3*The downstream effects of this may ultimately lead to increased caloric requirements for the entire organism. Although studies have not been replicated4 in humans, there may be an association due to the similarity in pathways shared between organisms.

Inositol:
Inositol is a sugar-like molecule, referred to as a sugar alcohol. Even though very similar in molecular structure to glucose, this molecule does not exhibit the traits that simple carbohydrates exhibit. Contrary to simple carbohydrates, this sugar alcohol has been shown to not actively increase adipose storage. In fact, Inositol has been found to decrease fatty acid synthase activity, a multi-enzyme protein that catalyzes fatty acid synthesis. This set of enzymes ultimately enables the body to produce triglycerides fat molecules that reside in adipose tissue (body fat).

Inositol may be effective in reducing insulin resistance, a common condition associated with increase adiposity (body fat).5*Insulin resistance, a condition to which your body becomes resistant to the activities of the hormone insulin. This condition leads to excess blood glucose levels and a host of symptoms and dysfunctions. A chemical called Inositol phosphoglycan is known to regulate the body’s sensitivity to insulin signaling. Inositol phosphoglycan structurally incorporates Inositol, thus inositol is required for this molecule to exert its regulating behavior.
The proper functioning and sensitivity to insulin is found in most healthy individuals, and is essential in maintaining overall health. Excessive exposure to blood glucose ultimately leads to insulin resistance and poor nutrient transport. Inositol may be effective in reducing this condition while at the same time reducing fatty acid (fat) synthesis.

Choline:
Choline is a simple molecule usually classified as a B vitamin. The B vitamin class is usually involved in the generation of energy and support of metabolism. Choline is an important precursor to the neurotransmitter acetylcholine. This neurotransmitter is involved in a host of activities, one of which includes muscular function and contraction. Acetylcholine is a fundamental neurotransmitter that enables the communication between neurons. Increased neural communication results in increased CNS activity which ultimately leads to increased energy expenditure. Energy expenditure requires nutrient input, either from stored energy (fat), or dietary nutrients. Choline exist in a delicate balance and homeostasis with methionine and folate. When these nutrients are not in balance adverse health effects may be present. Along with the increase in CNS activity comes increased cognitive ability, reported by many users. Choline may be effective as a nootropic, or a substance with ability to increase cognition. Increased neural cognition is thought to be due to choline’s role as a precursor to acetylcholine.
The supplementation of choline has been shown to reduce serum and urinary carnitine.

The reduction of carnitine in these fluids may indicate carnitine has been partitioned in tissues that utilize it as a fatty acid mitochondrial transport. When carnitine is used in the mitochondria it transports fatty acids to the location which they are broken down and used as energy. It has also been reported that molecular fragments of fat have been found in urine after carnitine and choline supplementation, which may be due to incomplete fatty acid oxidation and the removal of the subsequent byproducts.4*This means, choline supplementation may increase the utilization of carnitine and increase the removal of fatty acids, even though all fatty acids are not burned as energy. The fragments of fatty acids not burned as energy are extruded in the urine as molecular fragments.

What is this medicine used for? Lipotropic injections are used to help release fat deposits in some parts of the body. Some of these areas include the stomach, inner thighs, neck, buttocks and hips. Lipotropic, or fat burning, substances include methionine which helps the liver remove fat; inositol, similar to methionine; choline, which distributes cholesterol and prevents it from getting deposited in one part of the body. In some cases, a combination of these may be given. Injections can be administered up to twice a week. The amino acids that are injected into the body stimulate the liver into optimizing the process of metabolism. The injections are only effective temporarily. As soon as the effect of these substances wears out, the body starts returning to normal gradually. These are the same three ingredients that help with liver protection cocktail just in smaller dosages being an injectable.




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Ranger15
11-07-2019, 03:16 PM
Very interesting read thanks for putting this together. I’m all about progression of science and coming up with new supplements and medicines. For me personally one down side that I could see from this is that you would be adding even more injections. We’re already pinning daily and then if using HGH during blast even more. I’m sure for some this wouldn’t be problem . Is there anyway you could share some of your buddy’s lab work while using this ?

Primemuscle
11-07-2019, 06:01 PM
Nice post brother. Thanks for sharing


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Mattymoo
11-07-2019, 09:33 PM
Would be to see lab results and compare to Tudca lab results

chadmack282
11-07-2019, 11:38 PM
Great article
I have been pinning glutathione for quite a while but have no labs to compare.
Its the ultimate anti oxident so i pin MWF 50mg without orals & 75mg with orals. Without glute my urine would get a light brownish color toward the end of oral cycle with the glute there is no change in color even when orals r taken longer.
I pin it subq & after pinning there is like an ithing feeling at sight. Others say it burns but just an itching to me. I pin it at the same time as b-12 pin.

thebear
11-30-2019, 02:50 PM
Bump

Diesel1965
11-30-2019, 09:00 PM
Good read brother thank you for putting it up there.

Amjodo
04-03-2020, 07:56 PM
Good read.

I always use glutathione injections- 200mg m,w,f and TUDCA 500mg daily. Year round for the two.


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Trtquest
03-25-2021, 07:06 PM
Thx

Bobby38
04-13-2022, 06:48 PM
Going to try this. I just order some. My liver right now is a bit hi. I forget which but but both are around 76. I look up my values and post

ironjunkie777
10-05-2022, 01:31 PM
Bump great info


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Mr.Smith45
10-07-2022, 11:55 AM
MIC (pill or powder) is the old school liver cleaner that everyone swore by (pros), even Dr. Rand promotes it. They are dirt cheap. Right now I'm experimenting with the powder form, adding them to my post workout shake (I'm about 3 weeks off a cycle) I have been running this from the start, I'm going to get bloods in approx. 2 weeks so I'll see how it worked. I have done the Glute. and MIC injections after a cycle to clean everything up and it does work, I believe I pinned everyday though. Tests came back like I was never on anything.

*XXL
10-07-2022, 01:55 PM
MIC (pill or powder) is the old school liver cleaner that everyone swore by (pros), even Dr. Rand promotes it. They are dirt cheap. Right now I'm experimenting with the powder form, adding them to my post workout shake (I'm about 3 weeks off a cycle) I have been running this from the start, I'm going to get bloods in approx. 2 weeks so I'll see how it worked. I have done the Glute. and MIC injections after a cycle to clean everything up and it does work, I believe I pinned everyday though. Tests came back like I was never on anything.

Powder eh. I have used the inject before but haven’t in a while. From where?


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Mr.Smith45
10-07-2022, 02:34 PM
Powder eh. I have used the inject before but haven’t in a while. From where?


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ironjunkie777
10-09-2022, 09:55 PM
How would you dose the mic for injectable?


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Mr.Smith45
10-10-2022, 10:21 PM
How would you dose the mic for injectable?


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The compound I got from Aminos unlimited was, super lipo + mic + b&c complex, I pinned 1ml/day for a month. I also pinned glutathione 1ml/day for a month at the same time.

Anonymousbuilder96
03-03-2023, 07:09 PM
I have read a lot and people say TUDCA will raise your liver enzymes. Even when off everything but than I see people swear by it even when off of everything

bigadam73
03-05-2023, 07:56 PM
I’ve heard that glutathione needs to be shipped cold. Is there any truth to that?


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Mr.Smith45
03-05-2023, 08:21 PM
I’ve heard that glutathione needs to be shipped cold. Is there any truth to that?


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IDK, I've never had it shipped cold.