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View Full Version : Help Needed with this ROLLERCOASTER Ride (Side-by-side test results)



WatchWho
07-14-2020, 09:46 PM
Alright amigos!

I need some advice...
(side-by-side comparison image below)


Long story short...
l have been battling with the most frustrating spell of ED of my life. I have said it before - the libido and urge is there, but even a crazy dose of cialis ain't enough to consistently perform...

So... a little over a month ago, the labs revealed high SHBG (which had already been in the higher range of normal in the past) and high prolactin showing in my test results, so I got some caber and some proviron (and upped the test) to deal with these issues. As you will see below, the caber worked (too damn well) - and as a result, I am pulling back on the caber. The proviron, however - did not budge the needle, nor did the higher dose of test - when it came to the SHBG issue. I realize proviron only binds and would not necessarily drop the number.

BUT... My bedroom performance issues had only marginally improved for a brief period a couple weeks ago. And since relapsed...

With this current test result, I have no doubt that the SHBG is the big culprit.


And so you have the entire picture, let me bullet out what I know/don't know (and likely reasons for the high SHBG):



Quick stats: I am 40 years old. 6'3" / 210lbs / 33" waist / no clue on BF% (I am not fat, not skinny, no bulging 6 pack either - probably in range of 14-17%)
Current gear: 210mg/week Test cyp
Workout: 4 days a week (PPL/Full Body), and have been adding cardio to my regimen
Diet: Intermittent Fasting (20 hours per day)/Keto (helps with bullet point below)
As a child, I was given this wonderful gift called type 1 diabetes (I don't recommend it - it ain't as cool as you'd think)
Blood Glucose: Strictly controlled (avg BG range: 5-7)
Meds (not supps): Lantus Insulin (24 units per day), Humalog Fast Acting Insulin (~10-15 units per day on average), Metformin (1000mg/day), cialis (20mg/day)
Other health issues: November 2019 - kidney stones (blasted and passed)
Liver levels (as of May 2020) - all good
Kidney health (as of March 2020) - all good
Thyroid (as of June 2020) - all good
So... I am confident that the SHBG is NOT likely related to liver or thyroid problems
From research, it appears that elevated SHBG is one of the glorious special bonuses of being a Type 1 Diabetic (thanks Diabetes!)

In fact, there is an inverse relationship between how much insulin you take (for T1D) and the level of SHBG

In other words... lots of insulin shots = really fat with lower SHBG




Now the test results (the money shot):


59398

So... What can I do about this SHBG issue?



I am already taking boron, vitamin D, and all the other usual suspects (before this test)...

Since it isn't likely my liver/thyroid, there is no protocol option there...

I know large T levels can suppress SHBG but I really don't want my TRT/cruise dose to go any higher if I don't have to. In fact, I would prefer to titrate down from where I am...

Clearly proviron didn't make much of an impact for me...

And while increased insulin lowers shbg...


I can't take more insulin shots unless I want to deal with hypoglycemia and take a permanent vacation 6 feet under
Nor, do I wanna start binging on carbs and sugar just so I can take more insulin shots and live a hyperglycemic lifestyle of having feet amputated and being on dialysis down the road.



Do I just need to embrace some DHT compounds in my cruise/TRT?

These are the options I know of right now:



I do have a sh-t load of primobolan - it is DHT but I am not sure if that would suppress SHBG enough on its own
I also have a nice supply of Masteron P - again, if proviron didn't make it work - would mast?
I was already considering going on HGH (2iu/day). Some research suggests that it can lower SHBG...
I have about 200 tablets of syn anavar (10mg) - I read a lot of evidence of 5mg of winny doing the trick - perhaps 10mg daily of var would be the way to go.
I clearly prefer using orals like this in blasts/cycles. But it appears that to solve this will require an ONGOING protocol



Now... Please weigh in and help me solve this if you can...


Thanks so much.
I appreciate you taking the time to read this and share your feedback!








--

WatchWho
07-14-2020, 09:49 PM
And if the above image is not clear enough, here is an enlarged version...

Previous test
59399

Current test
59400

Riggs
07-14-2020, 09:58 PM
Just to kick this off....I'm on a long road trip so pls be patient w/me.

Exactly what are you experiencing that you're identifying as erectile dysfunction? Loss of libido - sex drive? Loss of feeling or stamina? Difficulty climaxing?

Type 1 or type 2? I'm gonna assume type 1?

How's your mental state of mind as in depression or anxiety?

Have you tried this OTC stack? It helps metabolize excess estrogen & aids in liver detoxification which further lowers*SHBG.

Indole-3-Carbinol
Calcium D-Glucarate
Choline/Inositol

WatchWho
07-14-2020, 10:19 PM
Just to kick this off....I'm on a long road trip so pls be patient w/me.

Exactly what are you experiencing that you're identifying as erectile dysfunction? Loss of libido - sex drive? Loss of feeling or stamina? Difficulty climaxing?

Type 1 or type 2? I'm gonna assume type 1?

How's your mental state of mind as in depression or anxiety?

Have you tried this stack?
Indole-3-Carbinol
Calcium D-Glucarate
Choline/Inositol

Thanks for the reply. As to your questions...



ED problem I have is NOT libido/desire/drive. I want it - I just can't maintain an erection and when I do - it is a semi erection. I have feeling and can climax. It's just not great not being able to stay hard. And it doesn't matter if I take 40mg of cialis (I even tried 60). And I can barely count on one hand how many times I have awakened with morning wood in the past 3-4 months...
I am Type 1 diabetic
Mental state: no depression or anxiety. I am generally in a decent mood (apart from my frustrations with bedroom performance - lol)
I do take Calcium D Glugarate 1000mg/day - but not the other supps mentioned...

Riggs
07-14-2020, 10:28 PM
Thanks for the reply. As to your questions...



ED problem I have is NOT libido/desire/drive. I want it - I just can't maintain an erection and when I do - it is a semi erection. I have feeling and can climax. It's just not great not being able to stay hard. And it doesn't matter if I take 40mg of cialis (I even tried 60). And I can barely count on one hand how many times I have awakened with morning wood in the past 3-4 months...
I am Type 1 diabetic
Mental state: no depression or anxiety. I am generally in a decent mood (apart from my frustrations with bedroom performance - lol)
I do take Calcium D Glugarate 1000mg/day - but not the other supps mentioned...


I encourage adding I3C & Inositol/Choline. It's a necessary stack IME. I'm sure I've lost the articles I had saved to substantiate this claim so I encourage you do your own homework. It's been yrs since I've researched this but as far as I remember the I/C supp provides a missing molecule necessary for binding estrogen in the elimination process. W/out it the estrogen can be re-absorbed.

Riggs
07-14-2020, 10:31 PM
Thanks for the reply. As to your questions...



ED problem I have is NOT libido/desire/drive. I want it - I just can't maintain an erection and when I do - it is a semi erection. I have feeling and can climax. It's just not great not being able to stay hard. And it doesn't matter if I take 40mg of cialis (I even tried 60). And I can barely count on one hand how many times I have awakened with morning wood in the past 3-4 months...
I am Type 1 diabetic
Mental state: no depression or anxiety. I am generally in a decent mood (apart from my frustrations with bedroom performance - lol)
I do take Calcium D Glugarate 1000mg/day - but not the other supps mentioned...


Ok

My 1st thought is high PL more so than high SHBG.

The T, DA, PRL & E2 relationship I have a good understanding of. So I can help adjust things there to gain a balance that'll boost libido/stamina. It might be better to understand SHBG expression & insulin resistance.

Lack of sensitivity and stamina. Have you tried any of these...

More frequent pins of T
Upping T while adding Asin (low dose)


What were your Caber and Proviron protocols?

thebear
07-14-2020, 10:35 PM
Of course it’s tough for us to really now. Things like under eating, liver stress, high prolactin and e2 can raise SHBG.

I haven’t used that lab so I am having a hard time seeing the norms, but I agree with Riggs on estrogen clearing.

Apologize but I forget, where you or are you on an AI?

For me I didn’t see any result in ED til my PL got to 1-2.

Another though is under eating. I am NOT a fan of keto or fasting one but, that’s me. I know your Type 1 DM but I still don’t agree it’s the answer and I have a strong hunch that this way of eating is playing a role.

There is lots of research around anorexia increasing SHBG. I know your not anorexia but I see fasting and keto as such.

That’s my 2c [emoji1317]

WatchWho
07-14-2020, 10:45 PM
Ok

My 1st thought is high PL more so than high SHBG.

The T, DA, PRL & E2 relationship I have a good understanding of. So I can help adjust things there to gain a balance that'll boost libido/stamina. It might be better to understand SHBG expression & insulin resistance.

Lack of sensitivity and stamina. Have you tried any of these...

More frequent pins of T
Upping T while adding Asin (low dose)


What were your Caber and Proviron protocols?


I pin every day and have all along.

As for the caber (which crushed my prolactin to below 10 miu/L) - I was taking .5 EOD. And I know that is CRAZY. In the time from my previous test, I was sure the prolactin was the issue and I kept titrating the dose up hoping the performance issues would improve. Obviously not the case.

I was taking 50mg/day of proviron.

I will also look into those supplements as well.

I am considering the option of upping test. I guess I only hesitate because (as you can see) from my earlier labs to now, I upped the test almost 20% and SHBG stayed the same (in fact, it went up a little bit - probably because I crushed my prolactin)...

Riggs
07-14-2020, 10:47 PM
And if the above image is not clear enough, here is an enlarged version...

Previous test
59399

Current test
59400

Bare with me as I explain this a little more the T, DA, PRL & E2 relationships. PLS DO YOUR OWN RESEARCH AS I'M NOT GONNA TAKE THE TIME TO LINK ALL THE SUBSTANTIATING EVIDENCE.

Our body has a natural pulse wherein it endogenously (natty) produces small amounts of Test in low doses. The issues most guys run in to with AAS is when they dose (pin) large amounts of T infrequently. This causes a chain reaction of negative sides and an imbalance of hormones.

The "rise" in Test stimulates DA (Dopamine) secretion at the receptor. Dopamine is known as the PIF (Prolactin Inhibiting Factor) and inhibits the PRL (Prolactin) secretion.

Now looking at it from the angle of high E2...the aromatase enzyme stops the "rise" in Test and as a result secretion of dopamine is inhibited. This allows for prolactin to spike as well. Also this is where libido crashes and you lose the ability to have an orgasm.

The operative word in the above is "rise". The "rise" in test, and it not being blocked by aromatization, is what causes the chain reaction that results in the natural hormonal balance. Our body has a pulse and releases hormones, or in this case Testosterone, in small amounts and in short intervals. So dosing ED with a low dose mimics the bodies natural pulse, yields the lowest possible sides by keeping you out of the diminishing returns zone and keeps aromatization at a minimum. Test is not down regulated, estradiol and Prolactin are kept low yielding less water retention (bloat) and allows for increased libido. This also yields an overall feeling of well being and reinforces the alpha male feeling we all love so much.

Now if you don't want to pin ED then I'll say something I've said a hundred times before....9 times outta 10 high PRL & high Estro go hand in hand. For this reason in the past I've stated PRL only "thrives" in an Estro rich environment.

Dial in your AI and run Caber. This gives you the best chance at not experiencing significant sides when pining high mg and only like once every 5-7 days (5-7 is*just as an example).

You can consider upping T but T1D being associated with high SHBG should logically yield high T. So I'd encourage more frequent low mg pins.

I need to know your Caber/Proviron protocols?
Adding an AI and the OTC stack I've suggested is a consideration as well.

Have you tried Citruline/Arganine/Beet root w/Bioperine for improved blood flow.

How is your heart health? Lipids? BP?

WatchWho
07-14-2020, 10:49 PM
Of course it’s tough for us to really now. Things like under eating, liver stress, high prolactin and e2 can raise SHBG.

I haven’t used that lab so I am having a hard time seeing the norms, but I agree with Riggs on estrogen clearing.

Apologize but I forget, where you or are you on an AI?

For me I didn’t see any result in ED til my PL got to 1-2.

Another though is under eating. I am NOT a fan of keto or farting one but, that’s me. I know your Type 1 DM but I still don’t agree it’s the answer and I have a strong hunch that this way of eating is playing a role.

There is lots of research around anorexia increasing SHBG. I know your not anorexia but I see fasting and keto as such.

That’s my 2c [emoji1317]

I am not on any AI at all.

As for the keto/IF. I hear ya and if I were not a T1D, would not have much argument with you. It is, for me, the best diet to manage my BG levels and keep them as controlled as I can.
When I was younger and eating a "balanced" diet, I was on a constant up and down with my BG levels. I'd eat something with carbs, not get the dose of insulin right and skyrocket up. Then, to fix it - take another shot (and over shoot it) and hit a hypoglycemic state. Then, to avoid dying from a hypo - I'd have to ingest fast acting glucose (or juice) and sky rocket up again. And the cycle repeats and is nasty business... Keto takes all the crap out of the equation for me.

Riggs
07-14-2020, 10:51 PM
I pin every day and have all along.

As for the caber (which crushed my prolactin to below 10 miu/L) - I was taking .5 EOD. And I know that is CRAZY. In the time from my previous test, I was sure the prolactin was the issue and I kept titrating the dose up hoping the performance issues would improve. Obviously not the case.

I was taking 50mg/day of proviron.

I will also look into those supplements as well.

I am considering the option of upping test. I guess I only hesitate because (as you can see) from my earlier labs to now, I upped the test almost 20% and SHBG stayed the same (in fact, it went up a little bit - probably because I crushed my prolactin)...

Well hell man you've peaked my interest now. I've helped a ton of guys over the yrs overcome ED issues thru finding their specific needs as far as hormone balance and blood flow. This is interesting asf. I'll continue to make myself available and do my best to help work thru this with you. I love a case like this!

WatchWho
07-14-2020, 10:54 PM
I pin every day and have all along.

As for the caber (which crushed my prolactin to below 10 miu/L) - I was taking .5 EOD. And I know that is CRAZY. In the time from my previous test, I was sure the prolactin was the issue and I kept titrating the dose up hoping the performance issues would improve. Obviously not the case.

I was taking 50mg/day of proviron.

I will also look into those supplements as well.

I am considering the option of upping test. I guess I only hesitate because (as you can see) from my earlier labs to now, I upped the test almost 20% and SHBG stayed the same (in fact, it went up a little bit - probably because I crushed my prolactin)...

Heart health/lipids (as of May 2020) - good
BP is usually around 112/70 (today was 108/77)

====

WatchWho
07-14-2020, 10:56 PM
Well hell man you've peaked my interest now. I've helped a ton of guys over the yrs overcome ED issues thru finding their specific needs as far as hormone balance and blood flow. This is interesting asf. I'll continue to make myself available and do my best to help work thru this with you. I love a case like this!

I appreciate it. And as has been the case with many of the challenges I have seen - the wildcard (as to why it don't make no damn sense sometimes) is motherf---ing type 1 diabetes! lol

thebear
07-14-2020, 10:57 PM
I am not on any AI at all.

As for the keto/IF. I hear ya and if I were not a T1D, would not have much argument with you. It is, for me, the best diet to manage my BG levels and keep them as controlled as I can.
When I was younger and eating a "balanced" diet, I was on a constant up and down with my BG levels. I'd eat something with carbs, not get the dose of insulin right and skyrocket up. Then, to fix it - take another shot (and over shoot it) and hit a hypoglycemic state. Then, to avoid dying from a hypo - I'd have to ingest fast acting glucose (or juice) and sky rocket up again. And the cycle repeats and is nasty business... Keto takes all the crap out of the equation for me.

Ok. What’s the window you eat in?

WatchWho
07-14-2020, 11:05 PM
5PM to 9PM. Truth be told, fasting "puritans" would argue that I cheat - because my morning coffee (5am) is a bulletproof coffee with MCT oil/butter. But I don't feel hungry throughout the day. And when my window opens, I do eat a lot of quality protein and fats. A typical dinner would be something like 8oz steak with 2 fistful servings of broccoli or cauliflower (drenched in butter, of course). And then I may have a couple snacks after that - including things like macadamia nuts, almond butter, or even a couple hard boiled eggs with avocados...

thebear
07-14-2020, 11:08 PM
5PM to 9PM. Truth be told, fasting "puritans" would argue that I cheat - because my morning coffee (5am) is a bulletproof coffee with MCT oil/butter. But I don't feel hungry throughout the day. And when my window opens, I do eat a lot of quality protein and fats. A typical dinner would be something like 8oz steak with 2 fistful servings of broccoli or cauliflower (drenched in butter, of course). And then I may have a couple snacks after that - including things like macadamia nuts, almond butter, or even a couple hard boiled eggs with avocados...

For me this is the biggest issue. But that’s my opinion. If you are keto but ate all day I bet you your SHBG would drop.

Riggs
07-14-2020, 11:14 PM
For me this is the biggest issue. But that’s my opinion. If you are keto but ate all day I bet you your SHBG would drop.

You a diabetic?

Good to have you chiming in.

Let's do this.

Helping others = life

thebear
07-14-2020, 11:17 PM
Lastly, metformin can increase SHBG.

thebear
07-14-2020, 11:17 PM
You a diabetic?

Good to have you chiming in.

Let's do this.

Helping others = life

I am not. Just know a thing or two, about a thing or two.

Riggs
07-14-2020, 11:22 PM
I am not. Just know a thing or two, about a thing or two.

Why I asked....


For me this is the biggest issue.

Riggs
07-14-2020, 11:25 PM
I am not. Just know a thing or two, about a thing or two.

And I know this......mannnn!

I've seen you be resourceful plenty.

Great job B...you're a valued member.

thebear
07-14-2020, 11:25 PM
And I know this......mannnn!

I've seen you be resourceful plenty.

Great job B...you're a valued member.

Same to you [emoji1317] I have learned a lot from your input.

WatchWho
07-14-2020, 11:32 PM
Dropping the IF might be needed. And I may try it if I need to. I just found some medical research about T1D and SHBG (unrelated to diet) suggesting the inverse relationship of insulin and SHBG being the reason tightly controlled (and completely out of control) diabetics having substantially high SHBG. And it seems that other T1Ds commonly have elevated SHBG levels (it is not unusual). That said, I won't rule out having to consider making a change like that if all other paths are blocked...

Here is some interesting stuff on it...

59401


Full article here... (https://ec.bioscientifica.com/view/journals/ec/2/1/18.xml)





Lastly, metformin can increase SHBG.

I really don't need the metformin. I take it for non-diabetes related purposes (it does have lots of benefits). But I might drop it for now...

thebear
07-14-2020, 11:40 PM
Lastly again lol, Boron can lower SHBG.

WatchWho
07-14-2020, 11:42 PM
Lastly again lol, Boron can lower SHBG.

I just upped my dose from 9mg to 15mg per day today. Why the hell not? haha
We shall see...

Riggs
07-15-2020, 12:02 AM
Dropping the IF might be needed. And I may try it if I need to. I just found some medical research about T1D and SHBG (unrelated to diet) suggesting the inverse relationship of insulin and SHBG being the reason tightly controlled (and completely out of control) diabetics having substantially high SHBG. And it seems that other T1Ds commonly have elevated SHBG levels (it is not unusual). That said, I won't rule out having to consider making a change like that if all other paths are blocked...

Here is some interesting stuff on it...

59401


Full article here... (https://ec.bioscientifica.com/view/journals/ec/2/1/18.xml)






I really don't need the metformin. I take it for non-diabetes related purposes (it does have lots of benefits). But I might drop it for now...

This is why I previously mentioned the below...


The T, DA, PRL & E2 relationship I have a good understanding of. So I can help adjust things there to gain a balance that'll boost libido/stamina. It might be better to understand the relationship of SHBG expression & insulin resistance & approach this from that angle.


You can consider upping T but T1D being associated with high SHBG should logically yield high T. So I'd encourage more frequent low mg pins.

Riggs
07-15-2020, 02:16 AM
I love this website....

Prolactin as an Adjunct for Type 1 Diabetes Immunotherapy | Endocrinology | Oxford Academic (https://academic.oup.com/endo/article/157/1/150/2251838)

WatchWho
07-15-2020, 02:59 PM
I love this website....

Prolactin as an Adjunct for Type 1 Diabetes Immunotherapy | Endocrinology | Oxford Academic (https://academic.oup.com/endo/article/157/1/150/2251838)

I will have to read this again when I am not multi-tasking. From first scan, it almost sounds like for TID, high prolactin is beneficial.
Well damn! If I have to avoid continued suppression of prolactin, there go all 19-nors... lol

Again... I need to re-read this when I am not distracted. Thanks for sharing!

Riggs
07-15-2020, 09:13 PM
I will have to read this again when I am not multi-tasking. From first scan, it almost sounds like for TID, high prolactin is beneficial.
Well damn! If I have to avoid continued suppression of prolactin, there go all 19-nors... lol

Again... I need to re-read this when I am not distracted. Thanks for sharing!

I had to share this because I'm not well versed on T1D and shit who knows man elevated PRL might be a good thing and us inhibiting it, especially significantly, could lead to further problems. And yes I'm reading it the same way.

It might be that 19nor's will come at a higher price to you as a diabetic.I get anxiety & high BP with EQ but IMO it's worth it.

I'm sure there are other ways to address the ED if stopping 19nor's doesn't remedy the issue.

I would love to know why Caber didn't lower PRL for you. Is it possible you have unusually low levels of DA....its something to consider IMO. DA is known as the PIF (Prolactin Inhibiting Factor) so this peaks my interest.

Aromatase does lower DA so I'm once again back to my suggestion of considering adding Asin.

WatchWho
07-15-2020, 09:18 PM
I had to share this because I'm not well versed on T1D and shit who knows man elevated PRL might be a good thing and us inhibiting it, especially significantly, could lead to further problems. And yes I'm reading it the same way.

It might be that 19nor's will come at a higher price to you as a diabetic.I get anxiety & high BP with EQ but IMO it's worth it.

I'm sure there are other ways to address the ED if stopping 19nor's doesn't remedy the issue.

I would love to know why Caber didn't lower PRL for you. Is it possible you have unusually low levels of DA....its something to consider IMO.

Truth be told, it has been a couple years since I touched any 19-nor compounds. But sucks because last month I picked up a big order of NPP that was planned for a future blast. Oh well...

Riggs
07-15-2020, 09:19 PM
Truth be told, it has been a couple years since I touched any 19-nor compounds. But sucks because last month I picked up a big order of NPP that was planned for a future blast. Oh well...

Hmmmm......

DA is known as the PIF (Prolactin Inhibiting Factor) so this peaks my interest.

Aromatase does lower DA, thru the mechanism of inhibiting the "rise" in T so I'm once again back to my suggestion of considering adding Asin.

Riggs
07-15-2020, 09:20 PM
Truth be told, it has been a couple years since I touched any 19-nor compounds. But sucks because last month I picked up a big order of NPP that was planned for a future blast. Oh well...

Then consider adding Caber again but I'd go with a more moderate dose of .5mg M/W/Sat. I believe it has a long ass half life of like 60 hours so the dose schedule is flexible.

WatchWho
07-15-2020, 09:22 PM
I would love to know why Caber didn't lower PRL for you. Is it possible you have unusually low levels of DA...

You might be looking at the older test (from before I took the caber). It DID. I took WAY TOO MUCH caber and crushed my PRL levels to near zero (as in the recent test from this week). In other words, .5 EOD caber = TOO DAMN MUCH!
So, I have pulled back on the caber.

Riggs
07-15-2020, 09:23 PM
You ever had your DHT level tested?

WatchWho
07-15-2020, 09:25 PM
You ever had your DHT level tested?

No. I have never tested it.

Riggs
07-15-2020, 09:26 PM
You might be looking at the older test (from before I took the caber). It DID. I took WAY TOO MUCH caber and crushed my PRL levels to near zero (as in the recent test from this week). In other words, .5 EOD caber = TOO DAMN MUCH!
So, I have pulled back on the caber.

Well shit yes I was. There you go. Yes .5mg EOD is a ton of Caber. While on a 19nor I run .5 M/Th/Sat and .5 M/Fr yr round.

Riggs
07-15-2020, 09:27 PM
No. I have never tested it.

That I'd like to see. Usually in the case of high SHBG we see low levels of sex hormones but in your case they are elevated.

This is definitely interesting.

WatchWho
07-15-2020, 09:34 PM
That I'd like to see. Usually in the case of high SHBG we see low levels of sex hormones but in your case they are elevated.

This is definitely interesting.

I will see what options I have to get that tested...
It sucks that labs are hard to use these days. I have been using mail labs recently. Since Canada has closed travel at the US border - I can't do my monthly drive across the border to the states to get my labs done the way I like. I could go on a rant but I do love the healthcare here in Canada, but getting Male Hormone labs in Canada, on the other hand - is a joke! US has a lab on every damn corner (Rant Over).

WatchWho
07-15-2020, 09:37 PM
Also... If I do want to ramp things up (and it may just verify it by non-scientific proof), what if I just added 10-20mg of Var to my daily regimen for a couple weeks? That is a DHT (that I have plenty of) that should suppress SHBG...
The non-scientific evidence being waking up with morning wood, of course! lol

Riggs
07-15-2020, 09:42 PM
Also... If I do want to ramp things up (and it may just verify it by non-scientific proof), what if I just added 10-20mg of Var to my daily regimen for a couple weeks? That is a DHT (that I have plenty of) that should suppress SHBG...
The non-scientific evidence being waking up with morning wood, of course! lol

Anecdotal evidence or what some call broscience w/out it we'd be 30 yrs back in the AAS/BB'n world. I don't know of a single Dr backed trial that studied the affects of running Test 500/Tren 500/Mast 800/Var 60mg ED......LMAO

I'm not much an advocate of adding too many things at one time as it can complicate figuring out what's doing what.

However you're need is urgent so I don't see any other issue with it other than what I mentioned above.

My head keeps coming back around to considering adding Aromasin.

WatchWho
07-15-2020, 09:56 PM
You referring to anecdotal evidence or what some call "broscience?" W/out it we'd be 30 yrs back in the AAS/BB'n world. I don't know of a single Dr backed trial that studied the affects of running Test 500/Tren 500/Mast 800/Var 60mg ED......LMAO

I'm not much an advocate of adding too many things at one time as it can complicate figuring out what's doing what.

However you're need is urgent so I don't see any other issue with it other than what I mentioned above.

My head keeps coming back around to considering adding Aromasin.

I know it is total bro science. Just can't help it.

I have plenty of aromasin. And my E2s aren't running low (they are on the upper mid normal range). So, I am open to it. Being that they are a suicide inhibitor and take longer to recover from a crash, I'd wanna avoid going too crazy. But I have it and will use it. How much would you go with to start?

Riggs
07-16-2020, 12:08 AM
I know it is total bro science. Just can't help it.

I have plenty of aromasin. And my E2s aren't running low (they are on the upper mid normal range). So, I am open to it. Being that they are a suicide inhibitor and take longer to recover from a crash, I'd wanna avoid going too crazy. But I have it and will use it. How much would you go with to start?

You can take up to 25mg ED safely IME.

BUT I encourage 12.5mg E3D & EOD is also IMO not overly aggressive either.

Man Asin being called the "suicide AI" is thrown around quite a bit but IME Adex shuts me down much harder than Asin. I love Asin over Adex dude. Especially for long term use.

I'm not considering Asin strictly based on estradiol levels. Adding Asin could yield higher DA which will inhibit PRL. That's what I'm focused on.

If we assume this is hormone related there are only a couple of ways to approach this.

Sounds like you've addressed blood flow with little/no success.
No heart is issues. Lipids are g2g.
No anxiety/depression.
No alcohol/substance abuse.
You're not obese.
BP is excellent. RHR is good.

Your on different units of measurement so I need to look those up in order to gauge your rate of T down regulation yah know.

Riggs
07-16-2020, 12:32 AM
So your T dose is 210mg & you're @ 851 ng/dl. Your Total T is @ 4 x dose. Not bad. The hormone is clearly there. But at that low dose I'd like to see 5 - 8 x dose.

59436

And wow after doing the conversion for estradiol man your E2 isn't bad at all. So consider Asin at 12.5mg E3D. Again for its influence on DA & PRL.

59437

Selfmadecloser
07-16-2020, 03:39 PM
Great thread guys! Thank you for positing!

WatchWho
07-16-2020, 07:21 PM
You can take up to 25mg ED safely IME.

BUT I encourage 12.5mg E3D & EOD is also IMO not overly aggressive either.

Man Asin being called the "suicide AI" is thrown around quite a bit but IME Adex shuts me down much harder than Asin. I love Asin over Adex dude. Especially for long term use.

I'm not considering Asin strictly based on estradiol levels. Adding Asin could yield higher DA which will inhibit PRL. That's what I'm focused on.

If we assume this is hormone related there are only a couple of ways to approach this.

Sounds like you've addressed blood flow with little/no success.
No heart is issues. Lipids are g2g.
No anxiety/depression.
No alcohol/substance abuse.
You're not obese.
BP is excellent. RHR is good.

Your on different units of measurement so I need to look those up in order to gauge your rate of T down regulation yah know.

I will add 12.5 of the aromasin E3D starting today.

FYI:
My RHR could be improved. I have recently upped my cardio routine (even though I am not the biggest fan) to address it. Currently, it averages around 80-85bpm...
I have also cut out all stims (other than one cup of coffee in morning).

Riggs
07-16-2020, 09:18 PM
I will add 12.5 of the aromasin E3D starting today.

FYI:
My RHR could be improved. I have recently upped my cardio routine (even though I am not the biggest fan) to address it. Currently, it averages around 80-85bpm...
I have also cut out all stims (other than one cup of coffee in morning).

Good deal.

Don't forget this OTC stack...
INDOLE-3-CARBINOL (I3C)
Calcium D-Glucarate (CD-G)
Inositol/Choline