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    Results 21 to 30 of 32

    Thread: Been running blaster exestane 25mg a day just got labs back

    1. #21
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      Quote Originally Posted by NevadaRage View Post
      Yes this was after a week of using 25 mg a day of there ADVANCED PHARMA AROMASIN - 25mg $100 PER 30 CAPS

      My bloods before are a couple pages down. Now there gear is legit but whatever this was did not cut 80% of estrogen it increased it.
      I'm questioning if this advanced pharma Aromasin I got in 2016 is any good....of course I don't have labs to prove anything. I'm on a pretty mild test only cycle right now (500mg/week cyp) and taking this aromasin eod at 12.5 (it's a hassle splitting up the capsules so if you find a source with tabs get those). I did have mid-cycle labs a year ago with no Estrogen blockers at 400mg/week Cyp and I was on the high end of the estrogen range at 41. Currently on this 500mg/week Cyp I thought I better break open the Aromasin and make sure I keep that estrogen down in check. Comparing current to previous cycle (when I was on 400mg/week with no estrogen blockers), and the fact these are cheap plastic caps filled with who knows what filler....my gut is making me think hmmmmm.....

      I know I can't compare Aromasin to previous Arimadex experience but I had some Geneza Anastrozle Arimadex before and that killed my estrogen....like no doubt it was working because it completely crashed it.

      Again, no labs or science to prove it but fwiw I'm comparing my body feelings to one year ago on 400mg/week no blockers to 500mg/week now with this aromasin 12.5 eod and if I had to guess it's not doing much if anything.

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      Been running blaster exestane 25mg a day just got labs back Been running blaster exestane 25mg a day just got labs back
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    3. #22
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      Aromasin is weak as hell . it was designed to keep a womens level of Testosterone (which is very low, like 50 ng/dl) from aromatizing into estrogen. it was NOT designed to keep estrogen in check with supraphysiological levels caused by AAS use. If estrogen control is a big concern then you need to be running something much more powerful like Arimidex or Letro, if gyno prevention is your biggest concern then simply run a low dose SERM like nolva while on cycle

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    5. #23
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      Quote Originally Posted by GearHeaded View Post
      Aromasin is weak as hell . it was designed to keep a womens level of Testosterone (which is very low, like 50 ng/dl) from aromatizing into estrogen. it was NOT designed to keep estrogen in check with supraphysiological levels caused by AAS use. If estrogen control is a big concern then you need to be running something much more powerful like Arimidex or Letro, if gyno prevention is your biggest concern then simply run a low dose SERM like nolva while on cycle
      First, sorry to original poster as I wasn't trying to hijack his thread. I just saw him throw out some experience with the Advanced Pharma APT Aromasin so I wanted to add my experience as well...

      If Aromasin is supposed to be weak as hell and not feel like it's doing a thing then I guess this Advanced Pharma is totally g2g....lol. And obviously I don't want Gyno! Growing boob tissue is always a scary thought! I'm always thinking hmmmm is that itchy nips or just my shirt... or one time I shaved my chest and thought I had gyno for sure because it was itchy....ha!


      Ok, joking aside, I'd say my concern is just keeping my Estrogen levels in the optimal range for my age group. Men at 30-39 years of age should be at 25.7 not as high as 41, which is where I was mid-cycle at 400mg/week Test Cyp.

      I was almost not going to do an estrogen blocker this cycle because the lab report I had said that "normal" male estrogen levels can range anywhere from 11 to 45 (so I thought I was fine at 41 or slightly higher). However, a friend on another forum showed me all the research that my age group really needs to be around 25.7 and why it's important to manage your estrogen closer to the "optimal" range for your age group. That's when I said to myself, ok it's time to pop open this bottle of Aromasin since it will expire in another few months anyways before I use it.

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    8. #24
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      Quote Originally Posted by texas.redneck View Post
      First, sorry to original poster as I wasn't trying to hijack his thread. I just saw him throw out some experience with the Advanced Pharma APT Aromasin so I wanted to add my experience as well...

      If Aromasin is supposed to be weak as hell and not feel like it's doing a thing then I guess this Advanced Pharma is totally g2g....lol. And obviously I don't want Gyno! Growing boob tissue is always a scary thought! I'm always thinking hmmmm is that itchy nips or just my shirt... or one time I shaved my chest and thought I had gyno for sure because it was itchy....ha!


      Ok, joking aside, I'd say my concern is just keeping my Estrogen levels in the optimal range for my age group. Men at 30-39 years of age should be at 25.7 not as high as 41, which is where I was mid-cycle at 400mg/week Test Cyp.

      I was almost not going to do an estrogen blocker this cycle because the lab report I had said that "normal" male estrogen levels can range anywhere from 11 to 45 (so I thought I was fine at 41 or slightly higher). However, a friend on another forum showed me all the research that my age group really needs to be around 25.7 and why it's important to manage your estrogen closer to the "optimal" range for your age group. That's when I said to myself, ok it's time to pop open this bottle of Aromasin since it will expire in another few months anyways before I use it.
      just a couple of quick points that may help you out

      if gyno is one of your big concerns then you simply can run 10mg of Nolva during your cycles, heck you may not even need an AI (pro's like Jordan Peters have been running their cycles this way for years).. a lot of times AI's have more negative side effects then the AAS drugs themselves. Half the time when a newb jumps on the forums complaining that they have no sex drive, no energy etc.. on their first cycle of only 400mg of test is not because of the test, its because the AI. I tell them to drop the AI and a week later they feel great.


      keeping your estrogen in the normal optimal range while OFF cycle is completely reasonable. but when on cycle the normal range of estrogen does not apply to us, it applies only to ''normal'' people, i.e., guys that produce natural test that puts them in a range of 250-900 ng/dl. When we are enhanced this 'normal' range does not apply to us because our test levels may be 5000-20,000 ng/dl . as test levels go up , estrogen is supposed to go up, thats how the body works.. when on cycle its more about balancing the RATIO of test to estrogen thats important, not trying to stay in the low normal range (you'll feel like shit trying to do that).. again we can simply run a SERM to prevent gyno and let our blood levels of estrogen elevate as test levels rise, if they get too too high, then sure we can add in an AI, but again we shouldn't attempt to stay low normal while on cycle (for contest prep this is a whole different thing).

      also Estrogen is key for building muscle.. it works much like human growth hormone does and accelerates sattelite cell proliferation in the muscle, also estrogen in the presence of high levels of androgens will dramatically increase your IGF levels and thus build much more muscle then one could with low estrogen. theres a reason that when cattle are injected with Tren they are injected with a shit ton of estrogen at the same time (high estrogen plus high androgen = a ton of growth).

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    10. #25
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      Quote Originally Posted by bigpapapumpaf View Post
      Aromasin will do NOTHING to combat the sides of tren.

      You need Caber to fight the prolactin which is what your estrogen is high from.

      BPP
      Now I do have caber on hand. I was only under the impression that caber is used to fight prolactin. "Breast milk" I don't have this problem but will use caber if it has other purposes. Thanks everyone also for helping me out. I'm learning allot. Things my pro physique coach didn't even tell me.

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    12. #26
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      I thought the aromasin wasn't working for me when I was taking it. The test and everything else works good.

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    14. #27
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      Jst gonna leave this here......

      Discussion

      We report the first detailed study of the pharmacological effects of exemestane in male subjects. Doses of 25 and 50 mg were comparable in suppressing all circulating estrogens and had similar effects of increasing serum androstenedione and testosterone concentrations. There were 38%, 71%, and 45% decreases in estradiol, estrone, and estrone sulfate concentrations, respectively, after 10 d, approximately 24 h after administration of the last dose of 25 mg exemestane, coupled with 60% and 32% increases in testosterone and androstenedione concentrations. The rise in the aromatase substrates, testosterone and androstenedione, is probably secondary to substrate accumulation and/or to the feedback increase in gonadotropins caused by aromatase blockade. The 21% decrease in SHBG concentrations caused by 25 mg exemestane confirms the observation in postmenopausal women (20).
      The maximum plasma concentration, time to achieve maximal concentrations and oral clearance for exemestane after oral administration of a single dose of 25 mg in the present study of males were similar to those reported for females (21–23). The terminal half-life in the present study (8.9 h) was considerably shorter than the published value of 27 h (23). The reason for this difference is not clear, but may be related to a true gender dependency possibly involving the volume of distribution (lower in males than females) and plasma or tissue protein binding (respectively, higher and lower in males). This finding may also be due to the lower sensitivity of the analytical methodology used in the previous studies (14 pg/ml by HPLC/RIA) (21).

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    16. #28
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      The maximal suppression evoked by exemestane at the single dose of 25 mg in the present study was similar to published results in postmenopausal women, but the time course differed (24). Evans et al. (24) reported that a single 25-mg oral dose of exemestane maximally suppressed estradiol concentrations by 72% 3 d after administration, and estradiol levels returned to baseline only 8–11 d after drug administration. In the present study maximal suppression of estradiol of 62% was observed 12 h after exemestane administration and returned to baseline 3–6 d after administration. The reason for this difference is not clear, but may be related to the shorter half-life of exemestane in males, the lower exposure to exemestane, and the higher levels of the aromatase substrates androstenedione (∼1 ng/ml in young males vs. ∼0.5 ng/ml in postmenopausal women), particularly the much higher testosterone concentrations in young males than in postmenopausal women (∼700 ng/dl vs. ∼20 ng/dl, respectively) (25). This is supported by the observation that in the 10-d study in young males reported here, the suppression of estradiol is weaker (due to the very high levels of the precursor testosterone) than that of estrone (due to androstenedione levels not very different from those in postmenopausal women). A limited suppression of circulating estradiol (∼50%) has been reported in a similar study in young males treated with 1 mg daily anastrozole (7), a dose that reduces estradiol by 85% in postmenopausal women (23).

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    18. #29
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      We conclude that exemestane is a potent aromatase inhibitor in men. Exemestane appears to be an alternative in the choice of inhibitors of the aromatase enzyme available for human studies. Further studies are underway to estimate dose and dosing intervals that will provide therapeutic suppression of estrogen concentrations in males. Long-term safety will also require further investigation.

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    20. #30
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      Ooops. I should have linked the study at the start. There are many more like this. Lets not write exemestane off right away bruthas

      Pharmacokinetics and Dose Finding of a Potent Aromatase Inhibitor, Aromasin (Exemestane), in Young Males | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic

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    22. Been running blaster exestane 25mg a day just got labs back
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    Been running blaster exestane 25mg a day just got labs back Been running blaster exestane 25mg a day just got labs back