Originally Posted by
Jozifp103
I'll try to say this in a way that makes sense lol. When you introduce exogenous test, your body obviously stops producing it's own. It does this by signaling the pituitary gland to stop producing LH (leutinizing hormone) and FSH (follicle stimulating hormone). LH signals the leydig cells in your testicles to produce testosterone. (i'm sure this is nothing new to you). What clomid/nolva will do is act on the pituitary itself and try to signal it to produce LH and FSH again so your testes will make testosterone. But at the same time, your pituitary is getting a "STOP" signal from the exogenous hormones. So now your pituitary is getting mixed signals which is never ideal.
Now with HCG you bypass the pituitary gland completely and just directly signal the testes to produce test. As we know HCG mimics LH, so regardless of the pituitary being shut down, the HCG will still be effective at keeping the testes working.
***edit: to address the "losing gains" subject, it has been shown that nolvadex has a negative impact on IGF-1 levels. This can sometimes be a substantial drop in natural IGF-1 levels (temporarily). This is believed to hinder gains. However, androgen use itself has a substantial increasing effect on IGF-1 levels, so I would assume it would cancel out any drop the nolva would cause.