Thread: Mk677- The No BS Straight Scoop ....

This is my first post here. Just wanted to share my experience with MK and possibly a way to make it a lot more effective. I ran it for a year straight, ending in Sept of this year. I dosed it at 20mg/ed for the first six month and took on about 8 lbs of water the first couple weeks but that eventually went away. I felt it helped a bit with recovery and retaining mass while doing EOD water fasting. Never lost any size and strength was still really good.

For the second half of the year I dissolved the MK in 99.9% pure DMSO and administered it sublingually at 10mg/ED. This is where it made a huge difference for me. Body fat steadily decreased and I got to the leanest I've probably ever been. But what made me really think this ROA was much more effective though, was that my arms started going completely numb during the night...I'm not talking about the occasional arm asleep kind of thing. I'm talking completely numb from the shoulder down every night...so numb that it was really painful when the blood started returning to the limb. This only started happening when I started the sublingual/DMSO ROA.

I know a lot of people don't like DMSO, but I thought some of you might like to give it a whirl and save a little money. I've read in some medical papers that MK's bioavailability is only around 30%. Can anyone confirm this? If so, the DMSO might be able to drastically increase the bioavailability. Anyway...if you can stand DMSO under your tongue for a few minutes it might help.

Originally Posted by PBandJ

This is my first post here. Just wanted to share my experience with MK and possibly a way to make it a lot more effective. I ran it for a year straight, ending in Sept of this year. I dosed it at 20mg/ed for the first six month and took on about 8 lbs of water the first couple weeks but that eventually went away. I felt it helped a bit with recovery and retaining mass while doing EOD water fasting. Never lost any size and strength was still really good.

For the second half of the year I dissolved the MK in 99.9% pure DMSO and administered it sublingually at 10mg/ED. This is where it made a huge difference for me. Body fat steadily decreased and I got to the leanest I've probably ever been. But what made me really think this ROA was much more effective though, was that my arms started going completely numb during the night...I'm not talking about the occasional arm asleep kind of thing. I'm talking completely numb from the shoulder down every night...so numb that it was really painful when the blood started returning to the limb. This only started happening when I started the sublingual/DMSO ROA.

I know a lot of people don't like DMSO, but I thought some of you might like to give it a whirl and save a little money. I've read in some medical papers that MK's bioavailability is only around 30%. Can anyone confirm this? If so, the DMSO might be able to drastically increase the bioavailability. Anyway...if you can stand DMSO under your tongue for a few minutes it might help.

If the absorption is so low in liquid and caps; why is the side effects so strong on 10-25mg like lethargy, appetite, and water retention? While doing this with DSMO did you get all the side effects too? Its possible since you've been on it for 6 months your body had adjusted.

I totally agree that since I'd been on it long term it was starting to work better (even if I didn't switch to DMSO). The numbness started nearly overnight though after trying the sublingual ROA in DMSO. I never really had a lot of sides on it other than the water retention in the beginning. I'm also not very sensitive to ghrelin due to water fasting on anabolics for cutting purposes. I can't confirm the 30% bioavailability either. I went digging through studies again and can't find any numbers. I hear a lot of people saying the bioavailability is high but I can't find any evidence of that. This is all in theory anyway. I don't have any bloods to confirm that it is a more effective ROA. Sure seemed like it though