I think IGF-1 LR3 dosed at approx. 100mcg per day (eod) can produce incredible results. I would use it in 10 x 10mcg micro injects in a weak body part and you should notice significant improvement if training and diet are optimal. I have yet to try our IGF-1 DES but hear good things. I know someone who is currently mutating who uses insane protocols such as approx. 50 micro injs of LR3 (rotated with DES) eod. Not something I would try but shows the difference IGF-1 can bring if you want it bad enough.