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  • Page 3 of 3 FirstFirst 123
    Results 21 to 22 of 22

    Thread: GH, IGF1 and should I combine them ?

    1. #21
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      I've been asked to specify more on this subject,

      Here for instance are a couple of references from scientific literature (I'll mark the conclusions with Bold) -

      - http://www.ncbi.nlm.nih.gov/pubmed/9129466
      ------------conclusions -
      GH and IGF-I combined further enhanced fat oxidation while reducing protein catabolism. Serum insulin concentrations were significantly increased by GH but decreased by IGF-I. GH significantly decreased serum total triiodothyronine concentrations and IGF-I significantly decreased serum corticosterone concentrations.

      - Effects of insulin-like growth factor-I and growth hormone in models of parenteral nutrition. - PubMed - NCBI
      -----------results and conclusions
      RESULTS:
      Administration of IGF-I, but not GH, attenuates dexamethasone-induced protein catabolism and increases insulin sensitivity. Simultaneous treatment with GH and IGF-I additively increases the serum concentration of IGF-I, whole-body anabolism, and lipid oxidation. GH or IGF-I when given alone produces similar increases in the serum concentration of IGF-I. However, GH selectively increases skeletal muscle mass whereas IGF-I selectively attenuates the intestinal atrophy and abnormal intestinal ion transport induced by TPN. These tissue-selective anabolic effects of GH and IGF-I are associated with differential increases in protein synthesis in skeletal muscle and jejunum, respectively.
      CONCLUSIONS:
      Simultaneous treatment with GH and IGF-I may offer the greatest clinical efficacy because of improved nitrogen retention in association with enhanced lipid oxidation and stimulation of protein synthesis in multiple tissue types.

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    3. #22
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      I've been asked many times by customers on insulin usage, with or without GH. Well the appropriate answer is IGF1. Considering this I would like to bump this interesting thread. IGF1 (Insulin Like Growth Factor) will help like insulin to shuttle amino acids and glucose to muscle cells, is far more anabolic then insulin, and posses a unique anti catabolic effect. Unlike exogenous insulin it increases insulin sensitivity hence enhances the pancreas abilities and health, and far safer then insulin which is problematic and tricky to use.

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    Page 3 of 3 FirstFirst 123

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