Combining IGF1 and Growth Together

[Zeus-Sr]

I just started supertropin and super IGF1. I am playing around with the timing and right now take GH in the morning and 2 hours before bed- I split the IGF pre and post workout.

I might try moving the IGF before bed for recovery purposes. If I did that I was thinking I might take the GH with it at the same time.

Is there anything negative about doing it that way


Taking IGF and GH Together

It would of course be expensive, but in theory there’s a lot to be said for combining growth hormone [structure shown below] and IGF-1, writes the Dutch endocrinologist Joop Janssen in an article in Reviews in Endocrine Metabolic Disorders. The article is worth looking at if you’re a chemical athlete.


The first argument that Janssen comes up with is that IGF-1 remains active for longer in the body if you inject it in combination with growth hormone. This is because IGF-1 is active for longer if it is attached to the binding protein IGFBP3. If you inject IGF-1 on its own, the production of this binding protein goes down. But if you inject growth hormone and IGF-1 together, the concentration of this binding protein increases. That might mean that you would have to inject less frequently, as IGF-1 breaks down quickly in the body.
A second argument is that growth hormone makes the cells ‘ignore’ insulin. As a result, blood sugar levels rise, as does the insulin level. In the long run this might not be so beneficial to health, and it would inhibit muscle growth. If you use IGF-1 together with growth hormone, then the muscle cells become more sensitive to insulin. And that would mean more muscle protein build-up.

[Primemuscle]

I just started supertropin and super IGF1. I am playing around with the timing and right now take GH in the morning and 2 hours before bed- I split the IGF pre and post workout.

I might try moving the IGF before bed for recovery purposes. If I did that I was thinking I might take the GH with it at the same time.

Is there anything negative about doing it that way


Taking IGF and GH Together

It would of course be expensive, but in theory there’s a lot to be said for combining growth hormone [structure shown below] and IGF-1, writes the Dutch endocrinologist Joop Janssen in an article in Reviews in Endocrine Metabolic Disorders. The article is worth looking at if you’re a chemical athlete.


The first argument that Janssen comes up with is that IGF-1 remains active for longer in the body if you inject it in combination with growth hormone. This is because IGF-1 is active for longer if it is attached to the binding protein IGFBP3. If you inject IGF-1 on its own, the production of this binding protein goes down. But if you inject growth hormone and IGF-1 together, the concentration of this binding protein increases. That might mean that you would have to inject less frequently, as IGF-1 breaks down quickly in the body.
A second argument is that growth hormone makes the cells ‘ignore’ insulin. As a result, blood sugar levels rise, as does the insulin level. In the long run this might not be so beneficial to health, and it would inhibit muscle growth. If you use IGF-1 together with growth hormone, then the muscle cells become more sensitive to insulin. And that would mean more muscle protein build-up.

I’m not familiar with the repercussions of taking igf1 and gh together. However I would think to be safe pin the gh a hour before the igf. That should give a grace period between the two and the gh will still be pulsing so the igf can bind to it and last longer


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[Sciroxx-lab]

You may check out here some general info on this subject - GH, IGF1 and should I combine them ?

Generally speaking GH will trigger both systemic and local IGF1 secretion with no connection to exogenous IGF1-lr3 (Somedin - this is the common used IGF1 product). IGF1-l3 has almost no affinity to the IGF binding proteins so it's fairly safe to use the GH and IGF1 in any given protocol, it's a matter of trial and error, and there are more then few proven protocols, one of them is the one that Seus-sr offered