Very informative read Beanlicker,..this is something a lot of people are unaware of


191aa vs. 192aa hGH, is there a difference?
Growth hormone consists of a 191 amino acid chain sequence, which is identical to endogenous (in the body) production of hGH by the anterior pituitary. Therefore, recombinant hGH should mimic the proper sequence chain so the body does not reject the hormone. However, most Chinese and one American manufacturer use an inferior manufacturing process to create biosynthetic growth hormone, essentially adding an extra amino acid to the sequence, creating a 192 amino acid chain.


This unnatural structure has been documented to increase the chance for developing antibodies to the hGH. What happens is the extra amino acid created antibodies that bind with the hGH molecule, interfering with the body’s ability to utilize the amino acid chain. The protein will be neutralized because the body sees the extra amino aicd as a foreign substance. When the body creates the antibodies, the hGH is rendered less effective, and will eventually stop working.


The FDA is currently working on banning all 192aa forms of hGH for sale in the US, due to the increased risk of developing antibodies, a severe problem for dwarfism, AIDS/HIV and other hGH deficient patients.