• Amused
  • Angry
  • Annoyed
  • ArrgPirate
  • atwork
  • Awesome
  • Bemused
  • Cocky
  • Cool
  • Crazy
  • Crying
  • deejayn
  • Depressed
  • Down
  • drinking
  • Drunk
  • eating
  • editing
  • Embarrased
  • Enraged
  • Friendly
  • gamingpc
  • gamingps
  • gamingsteam
  • gamingxbox
  • Geeky
  • Godly
  • Happy
  • hatemailing
  • Hungry
  • Innocent
  • lagging
  • livestreaming
  • loving
  • lurking
  • Meh
  • netflix
  • nostatus
  • Poorly
  • raging
  • Sad
  • Secret
  • Shy
  • Sneaky
  • Tired
  • trolling
  • Wtf
  • youtuber
  • zombies
  • Results 1 to 4 of 4

    Thread: GH effects, and what is the optimal length of usage ?

    1. #1
      Banned
      This user has no status.
       
      I am:
      ----
       

      Join Date
      Oct 2018
      Posts
      192
      Post Thanks / Like
      Rep Power
      719

      GH effects, and what is the optimal length of usage ?

      I encountered today an interesting inquiry from a member here concerning the proper usage in GH, I've been asked many times by customers the same questions - should it be used cycled ? or used year round ? is blasting with GH is effective ? better have some basic knowledge on the GH and its functioning -

      The GH-IGF1 is possibly the most complex hormonal axis in the human body. I'll try to offer some science based yet simple answers in a nutshell.

      GH has a direct and immediate metabolic effects - it releases glucose and fatty acids to the circulation, meaning it takes stored energy and make it available for the different organs and tissues, this is how it increases metabolism and burns fat both directly (taking fat stored fat and turning it to free fatty acids) and indirectly by expending calories and energy consumption. Note that releasing glucose to the circulation requires the body to secrete insulin immediately in order to balance the glucose levels and lower them back to normal, this mechanism leads with time to decreased insulin sensitivity, as when taking superpharmacological levels of GH the body needs to secrete constantly relatively high amounts of insulin. So GH increases insulin levels and decreases insulin sensitivity (which may bring to insulin resistance in extreme cases - diabetes)
      GH has a direct and immediate anabolic effect in the body - it causes different tissues (above all muscle) to retain nitrogen which leads to a positive nitrogen balance = anabolism. It also causes the body to retain minerals (sodium, potassium, calcium, phosphorus) as part of its anabolic effect as well, which explains the quite noticeable and fast water retention many users experience with GH.
      Having said and explained that many of the muscle building properties of GH are mediates by IGF1 which is considered the most anabolic hormone in the body. Even if we block somehow the IGF1 secretion which is induced by GH it'll still retain some of its anabolic and metabolic effects directly through GH receptors in different tissues, but big portion of the effect will be abolished, this is why in rare condition when short statue children don't respond well to GH treatment they're treated with IGF1 (prescribed Increlex - you my refer for some info for instance to Somedin (IGF1-lr3) vs Increlex (bio-identical IGF1)). The GH causes IGF1 secretion from target organs such as the liver and kidneys, and the IGF1 travels in the serum to different tissues (endoctine effect). The GH also causes a local section of IGF1 (and other growth factors) on different tissues, mainly on muscle tissue, it's called autocrine effect, and it's responsible on the stimulation of cell division, and this explains some of the unique so desired effect of GH (and IGF1).

      While the direct anabolic effects of GH are quite immediate (though not as prominent as the effects of anabolic steroids), the autocrine effect takes time and requires constant exposure to effective dosages.
      GH has another important effect - it directly triggers fibroblast activity, which means recuperation and creation of connective tissue, this of course enables optimal recuperation from injury, this trait enables better strength=muscle gains with time. Like the phenomena of new muscle fiber creation it the fibroblasts activity takes longer time to become pronounced, connective tissue is the slowest to be build and/or recuperate.
      The GH is used in the medical field as a short term anabolic aid for post trauma/surgery/severe-burns so yes short term of a couple of month certainly has its benefits, and will create some new muscle fibers to some extent, but as athletes knows GH really shines in long term usage
      Last edited by Pharmaca; 07-21-2019 at 12:49 AM.

    2. Thanks maxmuscle1, 9TMARE thanked for this post
      Likes maxmuscle1, 9TMARE liked this post
    3.    Sponsored Links

      ----
    4. #2
      Senior Member
      This user has no status.
       
      I am:
      ----
       
      maxmuscle1's Avatar
      Join Date
      Oct 2018
      Posts
      18,467
      Post Thanks / Like
      Rep Power
      675270
      Gh and Test! All the way!

      Max

    5. Thanks 9TMARE, Pharmaca thanked for this post
      Likes 9TMARE, RRR liked this post
    6. ----
    7. #3
      BOP VETERAN
      This user has no status.
       
      I am:
      Happy
       
      9TMARE's Avatar
      Join Date
      Jan 2019
      Posts
      6,291
      Post Thanks / Like
      Rep Power
      118445
      Appreciate the info!

    8. Thanks Pharmaca, maxmuscle1 thanked for this post
      Likes maxmuscle1 liked this post
    9. ----
    10. #4
      Junior Member
      is Blessed & Grateful
       
      I am:
      Awesome
       
      Black.Beard's Avatar
      Join Date
      Jul 2019
      Posts
      82
      Post Thanks / Like
      Rep Power
      123
      Depends on the application.


      For anti-aging, 1-2 IU or enough to get IGF-1 into the 200s-300s. Length of use: Forever.


      Best if started young (Early 30s before lower IGF-1 levels begin to negatively affect cells)

    11. Thanks maxmuscle1 thanked for this post
      Likes maxmuscle1 liked this post
    12. ----

    Similar Threads

    1. Replies: 0
      Last Post: 11-25-2017, 09:28 PM

    Tags for this Thread

    Bookmarks

    Posting Permissions

    • You may not post new threads
    • You may not post replies
    • You may not post attachments
    • You may not edit your posts
    •