*Symptoms are due to both the excess amount of growth hormone produced and by the mass itself (visual field defect, headache, etc). People with acromegaly have a gradual increase in the size of their hands and feet. ... Sometimes there is numbness, 'pins and needles' and pain in the hands, particularly around the thumb.

*Generally muscle/bone/nerve pain from growth hormone will diminish over time once stopped. Sometimes growth hormone will trigger carpal tunned syndrome which can linger for a longer period of time (months)after stopping growth hormone.

*Because growth hormone has the ability to increase muscle and tissue mass, it frequently causes compression of the nerves. The most common nerve compression syndrome induced by growth hormone is the carpal tunnel syndrome. The major nerve in the hand (median nerve) which travels down the arm is squeezed between the fibrous bands and the muscles in the hand. This painful condition causes tingling, numbness and weakness of the fingers and the hand.

Max