Thread: Type 2 Diabetic Question

I was Pre Diabetic and have now been diagnosed Type 2 Diabetic. I have a few kits of hGH and I was wondering from you knowledgeable Brothers if there was a way I could still use them without exasperating my situation? Like using it when hours from eating carbs or any scenario like that, or maybe I should just chuck em? That would be sad because I spent hard earned money on them and have done bloods on all of them that have all been good.

I read a study once for school that said if some predisposed it will make your condition worse. Another said it helps. I will try to find it.

Originally Posted by swolesoul

I was Pre Diabetic and have now been diagnosed Type 2 Diabetic. I have a few kits of hGH and I was wondering from you knowledgeable Brothers if there was a way I could still use them without exasperating my situation? Like using it when hours from eating carbs or any scenario like that, or maybe I should just chuck em? That would be sad because I spent hard earned money on them and have done bloods on all of them that have all been good.

Originally Posted by Marine

I read a study once for school that said if some predisposed it will make your condition worse. Another said it helps. I will try to find it.

I've read similar to what Marine has. If I'm remembering correctly, it stated that it seemed to help elderly diabetic patients lower blood glucose levels more so than
younger people. I thought it seemed odd because anybody I know that uses GH experiences higher than normal glucose levels. I'm curious as to what Marine finds in his school books.

Originally Posted by sauer

I've read similar to what Marine has. If I'm remembering correctly, it stated that it seemed to help elderly diabetic patients lower blood glucose levels more so than
younger people. I thought it seemed odd because anybody I know that uses GH experiences higher than normal glucose levels. I'm curious as to what Marine finds in his school books.

I have down time tomorrow and will try and find that case study

I can't find that case study. I'm going to drop by professors office after class tomorrow and ask her for some reading material I can reference.

GH treatment and glucose metabolism in GH deficient adults

The clinical presentations of GH-deficient adults are characterized by increased visceral adiposity, insulin resistance, dyslipidemia and hyperglycemia, which contributes to increased risk of cardiovascular morbidity and mortality [2]. Because IGF-1 has anti-inflammatory properties and is important for glucose uptake from peripheral tissues, metabolic disturbances in GH-deficient adults can be explained by the IGF-1 deficit [1]. A deprivation of GH-induced lipolysis and subsequent increased visceral adiposity are also involved in increased circulating FFAs and insulin resistance in these patients [2]. Most of the metabolic disturbances, including visceral adiposity, sarcopenia, hypertension, and dyslipidemia were reported to be relieved after GH treatment [1]. However, a number of studies suggested that there are possible negative impacts on glucose homeostasis such as impaired glucose tolerance as well as insulin sensitivity in patients with GH deficiency after GH administration. Notably, the interpretation of human studies regarding GH treatment and associated changes of glucose metabolism is intricate, because dosage and duration of GH as well as age, body mass index (BMI), and family history of diabetes in study participants can influence the study results.
The original dosage of GH treatment used in GH deficient adults were body weight-adjusted high dosing derived from the dosage used in GH deficient children, however this practice has changed to individualized dosing with lower doses to avoid adverse events of overtreatment since early 2000s. Many of the early studies using high GH doses (≥0.01 mg/kg/day) reported that fasting glucose and insulin levels increased after short-term GH treatment for less than 6 months, but were usually restored to baseline levels after 1 or 2 years of GH treatment (Table 1). GH treatment in high doses was effective for the reduction of total and visceral fat mass [21,22]. However, long-term GH replacement in high doses decreased insulin sensitivity and aggravated insulin resistance, which can be explained by the anti-insulin effects of GH. Despite increased insulin resistance, hemoglobin A1c (HbA1c) levels remained unchanged in both short-term and long-term treatment (Table 1).
Table 1.
Effects of recombinant human GH treatment on glucose metabolism in adults with GH deficiency


Low-dose GH administration in GH-deficient adults has been reported to be effective in improving body composition, albeit to a lesser degree than high-dose GH [23,24]. Most of the studies using low-dose GH treatment (<0.01 mg/kg/day) demonstrated no significant change or just a transient increase in fasting glucose levels (Table 1). Most of these studies reported unchanged insulin resistance and insulin sensitivity after long-term treatment with low-dose GH. Two studies conducted by the same investigators [25,26] showed an improvement of insulin sensitivity in GH-deficient patients with obesity after a short-term treatment with a fixed low-dose GH (0.1 mg/day). Most studies with low-dose GH treatment reported no significant changes in HbA1c levels, although a few studies showed a mild decrease in HbA1c within normal range in GH deficient adults [24]. One study investigated the effect of GH on fasting glucose levels and HbA1c in GH-deficient patients with pre-existing diabetes mellitus, and it revealed a mild elevation of fasting glucose without statistical significance and no aggravation of HbA1cvalues [23].
Recent studies assessed the risk of development of diabetes mellitus after low-dose GH treatment (Table 2). Because GH-deficient adults are at increased risk of impaired glucose tolerance compared to the general population, it is sufficient to compare the incidence of diabetes in GH treated patients with that of untreated patients. Currently, only one study with relatively short duration (2.3 years) reported that there was no increased risk of diabetes mellitus in GH-deficient adults after GH treatment compared with untreated GH-deficient controls [27]. Other studies compared the incidence of diabetes between GH treated patients and the normal general population, and most of them revealed no significant increase in the incidence of diabetes after 2–10 years of GH treatment (Table 2). One study demonstrated 2–6 times higher incidence of diabetes mellitus than expected in the normal general population [28]. It is noteworthy that increased age and BMI, female sex, and duration of GH, but not the dose of GH, were associated with increased risk of diabetes mellitus in this study

Originally Posted by swolesoul

I was Pre Diabetic and have now been diagnosed Type 2 Diabetic. I have a few kits of hGH and I was wondering from you knowledgeable Brothers if there was a way I could still use them without exasperating my situation? Like using it when hours from eating carbs or any scenario like that, or maybe I should just chuck em? That would be sad because I spent hard earned money on them and have done bloods on all of them that have all been good.

I posted a article for you above hope it helps. Sorry about the delay cramming for my last exam .

Originally Posted by Marine

I posted a article for you above hope it helps. Sorry about the delay cramming for my last exam .

No worries Brother I appreciate you taking the time!