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    Thread: 25mg MK677 bloodwork FAQ = 4iu pharm grade HGH (used 25mg mk677 for 6 months out of the year for 5 years straight with 7 bloodworks)

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      25mg MK677 bloodwork FAQ = 4iu pharm grade HGH (used 25mg mk677 for 6 months out of the year for 5 years straight with 7 bloodworks)

      Smont said:
      There is no amount of mk that will make it comparable to gh because they don't do the same thing. They have a few things in common but more things that make them completely different.
      I've taken 25mg MK66 powder in morning with coffee for 6 months out of the year, for 5 years now, and I've taken at least 7 blood works over the years (cost me nothing as it goes on my pre-loaded $1800 medical card), MK677 is highly effective for 8 months, when it then starts to dip a bit from the peak, it only looses slight effectiveness at that point as it is a derivative of GHRP-6. At that point (6 months, a little bit sooner than 8 months) is when I go off. I will then switch to peptides (remain effective indefinitely, but expensive) at that point for the next 6 months.

      1) Smont is correct in that it will not help you loose fat like HGH, BUT it has just as great if not greater nitrogen retention as 4iu of HGH, you can fast for long periods like I do (I eat in an 8 hour window, on a keto diet, and fast from 3pm till 7am next morning with cardio during the fast to maintain my 220lbs at 12% body fat), and never loose any muscle...just keeps piling on week after week). I also notice a 25 to 35% increase in strength over the many months I use it, compared to placebo, or the months I have not used it at all (no mk677, no peptides, nada). The studies on older folks also showed a 25% increase in strength in all leg press exercises in those who used it as well as compared to non-users.

      I actually went back on the mk677 at 25mg several days ago, gonna use for at least 6 months (July 2022 till end of January 2023)....will go back on the peptides after a long 6 month mk677 run.

      I alternate the two every 6 months so the mk677 stays 100% effective, go on the peptides for 6 months, then back on mk677...mk677 never loses any effectiveness this way. The peptides I use (100mcg mod grf 1-29 + 100mcg ipamorelin) x 3 times a day never loose effectiveness. I take one shot in morning, one before or after workout (before cardio on non workout days) and one shot before bed. Peptides can be used for life and never loose any effectiveness as this combo is NOT a derivative of GHRP-6. MK677 is dirt cheap compared to the peptides (around 120 a month for x 3 times a day for 30 days, and gives me very similar levels to the mk677)...I always save big time money on the 6 months I am on MK677 compared to the peptides.

      mase 1 said:
      I notice great muscle fullness on mk677. Do you notice a difference with ghrp/ipamorelin in regards to comparing muscle fullness?
      Yes, there is muscle fullness on the peptides, but the fullness on mk677 is even greater, like a dianabol feeling, super great nitrogen retention too. Really great mk677 pumps, very full indeed. The mk677 gives me the HGH of 4.0iu, I've done bloodwork on both mk677 and 4iu of pharm grade HGH, both the same.

      Benefits of MK677 I've noticed:
      1) releases your own natural stored up HGH in your brain that you still make plenty of when you are older, but due to the body programming the body for death as you get older, it does not release these huge stored up amounts anymore...MK677 puts the breaks on somatostatin so that these youthful levels of HGH can be released. Unlike HGH, MK677 is way less expensive, and you never have to worry about your body's natural production of HGH being shut down or diminished for very long periods of time which has been shown to happen if you take HGH daily for year or more straight. Even the brain's natural production of HGH has been shown to NOT HAPPEN if you take HGH during morning hours, studies show the night time HGH pulses are still suppressed.
      2) great nootropic effect on the brain = improved mood
      3) great sleep with longer time in REM sleep, better muscle building during sleep
      4) better energy all day.
      5) Skin looks younger due to greater collagen production,
      6) recover quicker from workouts, injuries and minor cuts
      6) increased lubrication of joints in gym due to same collagen increase
      7) nails and hair grow very fast. No lethargy at all for me, zero.
      8) truly do feel like an 18 year old on it. Best nootropic imho.

      I'm on a year round keto diet, so the water retention in the face is very minimal, and goes away completely along with the minor hunger pains after 2 to 3 weeks. Then it's smooth sailing. Mk677 sends my igf-1 from 225 to 370 or so igf-1.

      Daily 25mg takes me to the HGH output of a gifted 18 year old.

      Update: 2 days after being on 25mg a day mk677, feel great! crystal clear clarity in the brain, zero brain fog, feel great pump all day, increased endurance in gym and cardio on off day, really great mood, mega pumps during workout, great sleep, love the stuff! Will use from June 23, 2022 till end of December 2022 (6 months).
      ----------------------------------------------
      25mg MK677 bloodwork FAQ = 4iu pharm grade HGH (used 25mg mk677 for 6 months out of the year for 5 years straight with 7 bloodworks)

      Year 2018:
      ----------
      pic 1) 4-6-2018, baseline igf -1 = 227 ng/ml------------------------------------------baseline [227, high] (age 48, ref is 67 to 205 ng/mL)
      pic 2) 4-11-2018, 2 days on 4iu of Chinese pharm grade gh = 380 ng/ml----increase of 153 points
      washout period of 2 weeks off HGH
      pic 3) 4-25-2018, 2 weeks on mk677 only = 372 ng/ml----------------------------increase of 145 points
      pic 4) 9-7-2018, 6 months on mk677 only = 322 ng/ml----------------------------increase of 95 points
      pic 5) 11-2-18, 8 months on mk677 only = 304 ng/ml--------------------------------------increase of 75 points

      Start of new year 2019:
      ------------------------
      pic 6) 3-18-19, 4 weeks on mk677 only = 327 ng/ml-------------------------------------increase of 100 points, (2-22-19 thru 3-18-19)

      Start of new year 2020:
      -------------------------
      pic 7) 2-3-2020, 2nd baseline igf-1 reading = 229 ng/ml-----------------------------------baseline [229, high] (age 50, ref is 67 to 205 ng/ml)

      Notice how using MK677 for many years, did nothing to hurt my normal IGF-1, it read completely normal when I came off it for several weeks.

      372 ng/ml igf-1 is equivalent to 4.0 iu pharm grade GH from China, as 95 point raise per each 1iu of hgh for me (2 weeks)
      322 ng/ml igf-1 is equivalent to 3.4 iu pharm grade GH from China, as 95 point raise per each 1iu of hgh for me (6 months)
      304 ng/ml igf-1 is equivalent of 3.2 iu pharm grade GH from China, as 95 point raise per each 1iu of hgh for me (8 months)
      327 ng/ml igf-1 is equivalent of 3.5 iu pharm grade GH from China, as 95 point raise per each 1iu of hgh for me (4 weeks)

      So, in conclusion, being on mk677 for 2 weeks is similar to being on 4iu of Chinese pharm grade GH, for me anyhow, as the bloodtest proves it. Being on mk677 for 6 months is similar to being on 3.4iu of Chinese pharm grade GH. The Chinese pharm grade HGH I used was Supertropin (used in China to treat dwarfism).

      This is an incredible raise in igf-1 for my current age of 52 as reference is 67-205 for my age group, and the mk677 for 2 weeks brought me beyond the high range for a young adult in their early 20's.

      I couldn't be happier, this helps explain the increases in strength at the gym, as well as the fast recovery from workouts. Cardio on off days is a breeze. Not to mention mega pumps in the gym, a feeling of fullness all day in muscles, nootropic effects on brain of improved mood for me, enhanced energy all day, great sleep, zero lethargy for me everyday using it (I'm lucky in that aspect). I've even had rare days of less sleep due to schedule, and I still felt like a million bucks the next day being on mk677 as it gives you such great sleep with pleasant enhanced dreams many nights. As I am on a keto diet year round, there is minimal water retention in the face, both the minimal retention of water in face and hunger pains die down to zero after around 2 weeks on it, then it is smooth sailing.

      I've continued to take bloodwork every few months, and this 372 igf-1 then falls to around 325 igf-1 (equivalent to 3.4iu HGH) for the rest of the 8 months, still remaining at 325 by the 7 month, when it starts to fall slightly to 300 around month 8, but I get off after 6 months, as that is how long it remains 100% effective without dipping at all from the peak (6 to 7 months it reamains 100% effective). I've taken blookwork every 1 of the 4 years I have used it....my baseline was at 225 the 2nd year I took it (after being off mk677 for several weeks)...it once again took me to the exact same high levels of 4iu pharm grade HGH year after year, each of the 4 years, remains 100% effective year after year, and your baseline never changes from normal.

      --> The reason for the fall from 372 to 325 igf-1 is due to a "feedback loop" the body puts in place after being on mk677 for 3 weeks, in order to keep the levels from raising to high, the body will only maintain it at the HGH of around an 18 year old max.

      My only concern is that maybe around 25% of people (like myself) never experience any lethargy on MK67, zero lethargy...however from the reviews I have read the other 75% of people do experience lethargy on it, in which case I would recommend NOT using it, it's just not worth it if it makes you tired. Find something else to use like peptides or HGH then.

      MK677 should bring you to the high level of a young adult if you are already at the high end for an older adult.
      Older folks (59-225ug/L)
      young adult (116-358 ug/L)
      Attached Images Attached Images
      Last edited by evawinter; 06-26-2022 at 06:38 PM.

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      Pics 6 and 7 here:

      Start of new year 2019:
      ------------------------
      pic 6 at bottom) 3-18-19, 4 weeks on mk677 only = 327 ng/ml-------------------------------------increase of 100 points, (2-22-19 thru 3-18-19)

      Start of new year 2020:
      -------------------------
      pic 7 at top) 2-3-2020, 2nd baseline igf-1 reading = 229 ng/ml-----------------------------------baseline [229, high] (age 50, ref is 67 to 205 ng/ml)

      Notice how using MK677 for many years, did nothing to hurt my normal IGF-1, it read completely normal when I came off it for several weeks.
      Attached Images Attached Images
      Last edited by evawinter; 06-26-2022 at 06:15 PM.

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      Books to read on HGH "Grow young with HGH" by Dr. Ronald Klatz (5 stars, excellent) and "Human Growth Hormone, research and clinical practice" (has MK677 studies on dogs) by Roy Smith, Ph.D and Michael Thorner, MD.

      I go to waterpark with wife, her sister and teenage daughters once weekly with summer pass (where I used to lifeguard for many years), and a couple of times I've been stopped by groups of teenagers with workout questions, two weeks ago, a group of 4 teenagers stopped me and all said "woooahhh" in unison as they gazed at me and asked me questions....totally freaked me out, another time I was asked to take a pic with a group of girls, not used to attention. I blame the mk677 for helping to add dense muscle along with my normal 200mg testosterone cypionate TRT therapy weekly. You can increase your strength up to 35% in weekly periods beyond what you normally do when using it, and it keeps your joints lubricated just like HGH, welcome relief in the gym, and the mega pumps it gives you are great.

      smont said:
      Super valuable post!, Thank you for sharing that!!!, From what I seen. The benifits of mk are mostly geared towards building muscle or gaining weight, increased recovery. Not the fat burning, My igf-1 elevations we're also similar.
      Thank you kindly smont. I'm glad you also see similar igf-1 elevations.

      Reformednerd said:
      What are your thoughts on 12.5mg vs 25mg?
      Love your screen-name, LOL. Yes, 12.5mg is still highly effective, just checkout this attached study or see pic below: Ibutamoren - Wikipedia (study #9, page 4252)

      P.S. I do twice a year bloodwork with my doctor, completely normal bloodwork, liver values fine and best of all NORMAL BLOOD SUGAR, MK677 does not affect your blood sugar like high doses of HGH can. Studies show MK677 has ZERO effect on cortisol and prolactin, so no cortisol side effects: waking up early, stress, etc.

      attached 1: "Stimulation of the Growth Hormone (GH)-Insulin-Like Growth Factor I Axis by daily MK677" by 16 authors.
      attached 2: "Effects of a 7-day treatment with a novel, orally active, growth hormone (GH) secretagogue, MK-677 on young men"

      pic 1: GH and IGF-1 increase with mk677 compared to placebo
      pic 2: great books
      pic 3: Daily 25mg MK677 takes me to the HGH output of a gifted 18 year old.

      Last edited by evawinter; 06-26-2022 at 09:15 PM.

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      P.S. I inject my testosterone cypionate oil with an insulin syringe daily (20mg daily) into my shoulder, just like shaving or brushing teeth, part of the routine, my bloodwork is completely normal, stuff saved my life, literally, feel like a million bucks on it, sleep is great too. My doctor is also a bodybuilder, so that helps. He does all he can to improve your quality of life.

      I use a 29 gauge, 1ml, 1/2" insulin syringe to draw the testosterone cypionate oil from the vial, it takes a little longer for the oil to fill, as this is an insulin syringe, but it injects very fast...I will never go back to butt injections, etc. This is painless and easy.

      There is no increased cortisol release over normal...cortisol is virtually identical to placebo on high dose MK677, notice 219 vs 216 (25mg), and 216 vs 216 on low dose MK677 (12mg) I can cite 2 other studies that state the same.

      ReformedNerd said:
      If cycled for 6 months do you need 6 months off or how much time off is required?
      If you run MK677 for 6 months, then be sure to take off 5 months, then you can use it again, that's the way I've used it for years. If you use it for 8 months, then be sure to take off 5 months as well, then you can start it again, that way always remains 100% effective when you go back on it. Find something else to use on the 5 months off, like peptides or HGH.

      On the 5 to 6 months off MK677, I use a blend of 5mg mod grf 1-29 (cjc-1295 no DAC) + 5mg ipamorelin (100 mcg of each) x 3 times a day, 1st thing in morning, pre-workout or pre-cardio on non workout days, and pre-bed.

      This is my bloodwork after using the blend for 2 weeks, as you can see it took me to the IGF-1 range of better than most 18 year olds. I had the blood drawn at the local lab core approximately 1 hour after my first injection into skin pinch of my abdomen, I inject right under the skin subcutaneously x 3 times a day. Luckily, there was not much of a line of people in the morning, only 2 people in front of me. I go super early.

      5mg mod grf 1-29 + 5mg ipamorelin
      5000mcg (5mg) per vial
      add 2ml bac water in vial
      4iu (2 small tics, as each tic = 2iu) on a standard 100iu (1ml) insulin pin gives 100mcg of each
      4iu (4 small tics, as each tic = 1iu) on a 3/10 syringe insulin pin gives 100mcg of each
      Attached Images Attached Images
      Last edited by evawinter; 06-27-2022 at 12:29 PM.

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      Damn good info and experience. Never made it 6-8months on Mk677. I can gain weight the quickest on it though and like u compared it to dbol briefly, I agree. Full as fuck is how I describe it. Strong as damnit.

      It zaps me at first though and hell yea it makes me sleep deep lol. Overall I think it’s a great compound. I still run it on occasion. Good source pending of course

      Thanks bro
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      Great post popeye, yes, we are not the only ones to notice this, read of another comparing the strength gain to a similar dose of dianabol. Full as ***** is indeed how I describe it too.

      Sept 2018 labs (measured during 7month of taking mk677 daily) reveal labs to be completely normal for insulin sensitivity, and this was without taking +R-ALA or berberine. I have since added +R-ALA supplement the previous year & this year however (one before at least 2 of 3 meals). +R-ALA is also great post-workout, studies show the ability of +R-ALA to enhance insulin action on glucose metabolism in skeletal muscle, esp in those with some form of developed insulin resistance. As mentioned before, I'm on a year round keto diet, and have been for many years, and also fast from 3pm to 7am next morning, eat in an 8 hour window and run or do cardio during the fast (after 3pm).
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      I had to stop after 3 weeks. Week 1, 12.5mg/day, Week 2&3, 25mg/day. Couldn't take the water retention, feet and ankles blew up and my forearms would get so pumped, I couldn't maintain a grip on the bar.

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      MrSmith45 said:
      I had to stop after 3 weeks. Week 1, 12.5mg/day, Week 2&3, 25mg/day. Couldn't take the water retention, feet and ankles blew up and my forearms would get so pumped, I couldn't maintain a grip on the bar.
      Sorry to hear that MrSmith45. When I started up again a week ago at 25mg, I noticed only very minimal water retention in the face that completely went away after a few days, along with the minor hunger pains, now it is smooth sailing...keep in mind I'm on a year round keto diet, so that is probably why the water retention in the face was so very minimal, now I look completely normal 1 week later, no signs of any water retention in face, the muscles still feel very full however, mega-pumps in the gym.

      pickapec said:
      I worked in clinical labs from 1988 to 1993. What tregar posted is normal range. Gluconeogenesis will produce glucose from glucogenic amino acids and blood glucose will be in normal range. 90 is in the normal range. Now, I would not use MK677 for 5 years 6 months at a clip like OP has either but it seems to work pretty well for him. But hey, we are all risk takers or else we would not be on a PED board putting some very gray area **** in our bodies. OP at least has done the diligence to track blood better than probably 95% of people doing this stuff. His information is gold really.
      MK677 increases time in stage IV and REM sleep, greatly enhanced sleep, see 1st study "Effects of a 7 day treatment on young men...."

      According to attached study #2, you should take it in the morning for the greatest GH release, see pics.
      pic 17.JPG

      In conclusion, back in 2016, I found this brilliant article on MK677 on mindandmuscle.net, it has been preserved here:
      Attention Required! | Cloudflare
      After reading the article, 2 years later I bought some MK677 from China, and have used it ever since, and continue to buy it only from China. It's still dirt cheap from China, but here in the states it is marked up anywhere from x3 to x4 the China cost.
      Last edited by evawinter; 06-30-2022 at 09:52 PM.

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      FrankStyer said:
      If it increases GH then why wouldn't it help cause fat loss like GH - assuming calories are held equal?

      Would there be any reason to avoid carbs around administration? Would the body want to release GH when insulin/glucose is high?
      Thanks for kind words FrankStyer. I have actually found that on a keto diet, fat loss is accelerated beyond my normal keto diet and running x 3 times a week when taking MK677 contrary to the study that found there was no fat loss in subjects on a regular carb rich diet, so I disagree on the point that MK677 will not help with fat loss, so long as you follow a keto diet imho. Also, read the study above, by mindandmuscle.net author who lost 40lbs on it. Here is the study that found "Mean fat-free mass decreased in the placebo group but increased in the MK-677 group, however no significant differences were observed in abdominal visceral fat or total fat mass" ACP Journals

      P.S. Nitrogen retention is extraordinary on it, MK677 reverses diet-induced catabolism, just like the study below, for example, I fast from 3pm till 7am the next day to maintain my 220lbs, 12% bodyfat, eat only in an 8 hour window, consuming only a 20g casein shake in water at 7pm during fast period, and I have been able to avoid any muscle loss and consistently add muscle and improve strength week after week while losing even more fat with the keto diet + MK677, a study on older adults showed a 25% increase in strength in un-trained very old adults (60 years old) on leg press exercises, however, in my experience, there is up to a 35% increase in strength in weight trained athletes like myself (I keep a weekly workout journal).

      Like a member once posted, the strength gains on it can be compared to dianabol, I totally agree, there is an all day fullness in the muscles and mega pumps in the gym. Keep in mind my protein intake is around 1.2g per lb of body weight, use 6g CLA daily combined with 1.25g betaine before each meal, chromium picolinate, fish oil, daily 50g MET-rx protein plus shake or pudding with added 25g casein = 75g, HMB x 8g a day, HMB + BCAA's before cardio (20 minute run) to also help prevent any muscle catabolism.


      MK677 Increases Muscle Mass in arms and legs of older 60 to 81 year old adults, 25% increase in strength: An Anti-frailty Pill For Seniors? New Drug Increases Muscle Mass In Arms And Legs Of Older Adults -- ScienceDaily

      Attached Images Attached Images
      Last edited by evawinter; 07-01-2022 at 02:31 PM.

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      On the 5 to 6 months off MK677, I use a blend of 5mg mod grf 1-29 (cjc-1295 no DAC) + 5mg ipamorelin (100 mcg of each) x 3 times a day, 1st thing in morning, pre-workout or pre-cardio on non workout days, and pre-bed

      This is my bloodwork after using the blend for 2 weeks, as you can see it took me to the IGF-1 range of better than most 18 year olds, a remarkable 406 ng/ml IGF-1. I had the blood drawn at the local lab core approximately 1 hour after my first injection into skin pinch of my abdomen, I inject right under the skin subcutaneously x 3 times a day. Luckily, there was not much of a line of people in the morning, only 2 people in front of me. I go super early.

      For those who suffer lethargy on MK677, there is hope, just use the peptide blend.

      Peptide Calculator - Reconstituting Bodybuilding Peptides (basskilleronline.com)


      5mg mod grf 1-29 + 5mg ipamorelin
      5000mcg (5mg) per vial
      add 2ml bac water in vial
      4iu (2 small tics, as each tic = 2iu) on a standard 100iu (1ml) insulin pin gives 100mcg of each
      4iu (4 small tics, as each tic = 1iu) on a 3/10 syringe insulin pin gives 100mcg of each
      Attached Images Attached Images

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