Plastic bottle top filters simply don’t work for our purposes. Full stop. The first time you brew purple Tren because the blue plastic leeched into the solution, you’ll never use them again. I bought a case and tossed 8 of them once I figured that out. Just because your batch doesn’t turn blue doesn’t necessarily mean you aren’t pinning plastic anyway.

All glass is the way to go for small batches but even at 300ml, using capsule filters and a peristaltic pump only increases your consumables cost by $2/vial. Negligible for the peace of mind.
Vacuum is too slow and there are too many variables in where you can introduce pathogens, IMO.