I have been reading a lot more into the affects antidepressants can have on your pct meds like nolvadex.
Below is a chart of some meds and their affects with nolvadex.
Antidepressant Drug Interaction with Tamoxifen Safety Range
Paxil (paroxetine)
Prozac (fluoxetine)		 Prevents antiestrogen benefit Avoid Use
Cymbalta (duloxetine)
Wellbutrin (bupropion)
Zoloft (sertraline)		 Medium interference with antiestrogen benefitNote: Studies confirm that Zoloft interferes with Tamoxifen. Increases Risk
Saint John's Wort
(hypericum)		 Modest inhibition of antiestrogen benefit Increased Risk
Celexa (citalopram)
Lexapro (escitalopram)
Pristiq (desvenlafaxine)
Remeron (mirtazapine)		 Mild interactionNote: Pristiq and Remeron have not been well-studied for interaction with Tamoxifen. Slight Risk
Black Cohosh
(Actaea)		 May enhance the antiestrogen benefitNote: There are just a few studies for interaction with Tamoxifen. Slight Risk
Effexor (venlafaxine) Almost no interaction with Tamoxifen Best Choice
Sources: