Thread: Safety profile of caffeine and 1,3-dimethylamylamine supplementation in healthy men.

Interesting study I notice the media that has been bashing DMAA has not picked up this one to run with it....

Safety profile of caffeine and 1,3-dimethylamylamine supplementation in healthy men.




Abstract
Caffeine and 1,3-dimethylamylamine (DMAA) are widely used alone and in combination with dietary supplements. No investigation has determined the safety profile of chronic intake of caffeine or DMAA, alone or in combination, within the same study design. A total of 50 young and healthy men completed 12 weeks of daily supplementation with either a placebo (n = 11), caffeine at 250 mg day(-1) (n = 14), DMAA at 50 mg day(-1) (n = 13), or caffeine at 250 mg day(-1) + DMAA at 50 mg day(-1) (n = 12). Before and after 6 and 12 weeks of supplementation, the following variables were measured: body mass/composition, resting respiratory rate, blood pressure, 12-lead electrocardiogram, urinalysis, complete blood count, metabolic panel, lipid panel, and oxidative stress, inflammatory, and cardiac biomarkers. No interaction effects were noted for any variable (p > 0.05), with little change occurring across time for subjects in any of the four conditions. With the exception of urinary pH (p = 0.05; Pre (6.5 ± 0.1) higher than week 6 (6.1 ± 0.1)) and blood CO(2) (p = 0.02; week 12 (25.9 ± 0.3 mmol L(-1)) higher than week 6 (24.8 ± 0.3 mmol L(-1))), no time effect was noted for any other variable (p > 0.05). These data indicate that 12 weeks of daily supplementation with caffeine and DMAA, alone or in combination, does not result in a statistically significant change in any of the measured outcome variables.

http://www.ncbi.nlm.nih.gov/pubmed/23424215

The people that are abusing dmaa will ruin it for everybody. The chick that died in the marathon was said to have taken jack3d "a couple of times" before the race. I also had a guy tell me he takes a couple scoops before he hits the bars on the weekends.

Originally Posted by Johnson

The people that are abusing dmaa will ruin it for everybody. The chick that died in the marathon was said to have taken jack3d "a couple of times" before the race. I also had a guy tell me he takes a couple scoops before he hits the bars on the weekends.

Nice, a heart attack cocktail. After a couple of yagerbombs and redbull+vodkas boom goes the dynamite.

Originally Posted by drednought

Nice, a heart attack cocktail. After a couple of yagerbombs and redbull+vodkas boom goes the dynamite.

Natural selection at its best! This country needs to stop trying to "save people" from themselves...