Thread: HRT/TRT--The basics (by Tulane University Medical Center)

Intramuscular injection

Testosterone cypionate and enanthate are frequently used parenteral preparations that provide a safe means of hormone replacement in hypogonadal men. Testosterone is esterified to inhibit degradation and to make it soluble in oil-based injection vehicles that retain the drug in muscle tissue. In men 20-50 years of age, an intramuscular injection of 200 to 300 mg testosterone enanthate is generally sufficient to produce serum testosterone levels that are supranormal initially and fall into the normal ranges over the next 14 days. Fluctuations in testosterone levels may yield variations in libido, sexual function, energy, and mood. Some patients may be inconvenienced by the need for frequent testosterone injections.11 Increasing the dose to 300 to 400 mg may allow for maintenance of eugonadal levels of serum testosterone for up to three weeks, but higher doses will not lengthen the eugonadal period.12

Does this section somewhat imply that one should be injecting in overlapping intervals? For example: If test e is used weekly at 300 mgs. per dose, if one injection is on a Monday should the next one be on Sunday and continue a pattern of every six days or less? I'm still trying to educate myself instead of going solely by feel. Thanks.

Originally Posted by slash75cmd

Intramuscular injection

Testosterone cypionate and enanthate are frequently used parenteral preparations that provide a safe means of hormone replacement in hypogonadal men. Testosterone is esterified to inhibit degradation and to make it soluble in oil-based injection vehicles that retain the drug in muscle tissue. In men 20-50 years of age, an intramuscular injection of 200 to 300 mg testosterone enanthate is generally sufficient to produce serum testosterone levels that are supranormal initially and fall into the normal ranges over the next 14 days. Fluctuations in testosterone levels may yield variations in libido, sexual function, energy, and mood. Some patients may be inconvenienced by the need for frequent testosterone injections.11 Increasing the dose to 300 to 400 mg may allow for maintenance of eugonadal levels of serum testosterone for up to three weeks, but higher doses will not lengthen the eugonadal period.12

Does this section somewhat imply that one should be injecting in overlapping intervals? For example: If test e is used weekly at 300 mgs. per dose, if one injection is on a Monday should the next one be on Sunday and continue a pattern of every six days or less? I'm still trying to educate myself instead of going solely by feel. Thanks.

i think you will be better with less but a every 4 day you will have a more stable test level in you with less fluctuation...

Originally Posted by korsaire

i think you will be better with less but a every 4 day you will have a more stable test level in you with less fluctuation...

I run .6 ml per week. My bottle is a 250mg/ml. I shoot .2 ml EOD sub q. Yes every other day under the skin. I use a slin pin that's 27g. Research suggests sub q allows better absorption. I will vouch for that because I used to be on .75 per week and my levels were around 900-1000. Now I run .6 EOD and levels run 1026.
Just food for thought.


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Originally Posted by Robocop_9

I run .6 ml per week. My bottle is a 250mg/ml. I shoot .2 ml EOD sub q. Yes every other day under the skin. I use a slin pin that's 27g. Research suggests sub q allows better absorption. I will vouch for that because I used to be on .75 per week and my levels were around 900-1000. Now I run .6 EOD and levels run 1026.
Just food for thought.


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Mine is 200 mg / ml roughly 75 to 80 on mon and fri.

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Originally Posted by Robocop_9

I run .6 ml per week. My bottle is a 250mg/ml. I shoot .2 ml EOD sub q. Yes every other day under the skin. I use a slin pin that's 27g. Research suggests sub q allows better absorption. I will vouch for that because I used to be on .75 per week and my levels were around 900-1000. Now I run .6 EOD and levels run 1026.
Just food for thought.


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So you're running at least 1.8ml per week and your levels are only 1026? Something is off.....

Originally Posted by Xtreme4Life

So you're running at least 1.8ml per week and your levels are only 1026? Something is off.....

No. That's my bad. I run .6 every week. Pin .2 EOD.


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