I've been on trt for 5 years. For the first four, my E2 numbers were in the mid-60s and never had any issues. Over the last year, I noticed my libido dropping, so I decided to do more blood work. My E2 had risen to the low 80s. I've never had much luck with DIM or Calcium d-Gluterate. I played around with various Exemestane dosages and ended up at 12.5 mg every 5th day. That put me an E2 of 45 with a total T of 1500. Libido Sky High and also leaning me out a bit. I was already sub 10%, but apparently, I was holding a lot of some cutaneous water that I didn't realize.